Abstract
The article to which this Corrigendum refers was published in Human Mutation 39(12): 1901–1915 (https://doi.org/10.1002/humu.23602). Authentication analysis at Coriell Institute for Medical Research (Camden, NJ) revealed that the iPSC line named HFF in the article was not derived from a control individual but from cells of a female patient with osteogenesis imperfecta (GM17602/GM17604), carrier of a heterozygous missense mutation (p.G700C; NM_000089) in the COL1A2 gene. Differentiated neurons from HFF were genome-edited and used to examine mitochondrial transport in iPSC-derived neurons in figure 6. For these experiments, the line was used as an isogenic pair with and without heterozygous TUBB4A knockout. Mutations in the COL1A2 gene have not been associated with neurodegenerative diseases and the symptoms of neurological movement disorders have not been described for osteogenesis imperfecta. Therefore, the correction does not alter the interpretation of the results as discussed in the paper. The authors wish to apologize for the incorrect description of an iPSC line in the paper.
Original language | English |
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Journal | Human Mutation |
Volume | 40 |
Issue number | 12 |
Pages (from-to) | 2444 |
Number of pages | 1 |
ISSN | 1059-7794 |
DOIs |
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Publication status | Published - 01.12.2019 |
Research Areas and Centers
- Research Area: Medical Genetics