Corrigendum to: Motor protein binding and mitochondrial transport are altered by pathogenic TUBB4A variants (Human Mutation, (2018), 39, 12, (1901-1915), 10.1002/humu.23602)

Franca Vulinovic, Victor Krajka, Torben J. Hausrat, Philip Seibler, Daniel Alvarez-Fischer, Harutyun Madoev, Jin Sung Park, Kishore R. Kumar, Carolyn M. Sue, Katja Lohmann, Matthias Kneussel, Christine Klein, Aleksandar Rakovic

1 Citation (Scopus)

Abstract

The article to which this Corrigendum refers was published in Human Mutation 39(12): 1901–1915 (https://doi.org/10.1002/humu.23602). Authentication analysis at Coriell Institute for Medical Research (Camden, NJ) revealed that the iPSC line named HFF in the article was not derived from a control individual but from cells of a female patient with osteogenesis imperfecta (GM17602/GM17604), carrier of a heterozygous missense mutation (p.G700C; NM_000089) in the COL1A2 gene. Differentiated neurons from HFF were genome-edited and used to examine mitochondrial transport in iPSC-derived neurons in figure 6. For these experiments, the line was used as an isogenic pair with and without heterozygous TUBB4A knockout. Mutations in the COL1A2 gene have not been associated with neurodegenerative diseases and the symptoms of neurological movement disorders have not been described for osteogenesis imperfecta. Therefore, the correction does not alter the interpretation of the results as discussed in the paper. The authors wish to apologize for the incorrect description of an iPSC line in the paper.

Original languageEnglish
JournalHuman Mutation
Volume40
Issue number12
Pages (from-to)2444
Number of pages1
ISSN1059-7794
DOIs
Publication statusPublished - 01.12.2019

Research Areas and Centers

  • Research Area: Medical Genetics

Fingerprint

Dive into the research topics of 'Corrigendum to: Motor protein binding and mitochondrial transport are altered by pathogenic TUBB4A variants (Human Mutation, (2018), 39, 12, (1901-1915), 10.1002/humu.23602)'. Together they form a unique fingerprint.

Cite this