Three different clarifications are warranted to better understand our findings and conclusions. (1) On page 9 in the PDF version, subtitle “Medium acidification has less influence on Ca2+ regulation” should instead read: Role of Asc-induced acidification in increasing Ca2+ influx Section summary clarification: The role was reevaluated of Asc-induced medium acidification in contributing to increases in Ca2+ influx. We wish to clarify that the responses to Asc were much larger than those induced by medium acidification. Therefore, lowering the pH does not account for how Asc increases intracellular Ca2+ influx. (2) Subtitle for Fig. 10 should be corrected as: Acidifying-induced Ca2+ transients in etoposide-resistant and -sensitive WERI-Rb1 cells (3) The following alteration is more precise regarding the role of TRPV1 channel activation during medium acidification. (page 11 - paragraph 2 and page 14 - paragraph 3; PDF version): Section summary clarification: TRPV1 activation does not contribute to the small increases in Ca2+ influx resulting from medium acidification. This channel is not involved since the decline in pH occurred over a range known not to alter its activity. We suggest that mechanisms other than acidification are the main contributors underlying Asc–induced Ca2+ transients. Moreover, WERI-Rb1 cells possibly possess other pH sensitive pathways since lowering the pH induced significant increases in Ca2+ influx. These corrections do not affect the results and conclusions of the article. All authors agree with the corrections.