Contrast-enhanced cardiac MRI before coronary artery bypass surgery: Impact of myocardial scar extent on bypass flow

Peter Hunold; Parwis Massoudy; Claudia Boehm; Thomas Schlosser; Kai Nassenstein; Stephan Knipp; Holger Eggebrecht; Matthias Thielmann; Raimund Erbel; Heinz Jakob; Jörg Barkhausen

doi:10.1007/s00330-008-1066-y

Contrast-enhanced cardiac MRI before coronary artery bypass surgery: Impact of myocardial scar extent on bypass flow

Peter Hunold^*, Parwis Massoudy, Claudia Boehm, Thomas Schlosser, Kai Nassenstein, Stephan Knipp, Holger Eggebrecht, Matthias Thielmann, Raimund Erbel, Heinz Jakob, Jörg Barkhausen

^*Corresponding author for this work

Abstract

The aim of the study was to relate the extent of myocardial late gadolinium enhancement (LGE) in cardiac MRI to intraoperative graft flow in patients undergoing coronary artery bypass graft (CABG) surgery. Thirty-three CAD patients underwent LGE MRI before surgery using an inversion-recovery GRE sequence (turboFLASH). Intraoperative graft flow in Doppler ultrasonography was compared with the scar extent in each coronary vessel territory. One hundred and fourteen grafts were established supplying 86 of the 99 vessel territories. A significant negative correlation was found between scar extent and graft flow (r=-0.4, p<0.0001). Flow in grafts to territories with no or small subendocardial scar was significantly higher than in grafts to territories with broad nontransmural or transmural scar (75±39 vs. 38±26 cc min^-1; p<0.0001). In summary, the extent of myocardial scar as defined by contrast-enhanced MRI predicts coronary bypass graft flow. Beyond the probability of functional recovery, preoperative MRI might add value to surgery planning by predicting midterm bypass graft patency.

Original language	English
Journal	European Radiology
Volume	18
Issue number	12
Pages (from-to)	2756-2764
Number of pages	9
ISSN	0938-7994
DOIs	https://doi.org/10.1007/s00330-008-1066-y
Publication status	Published - 26.06.2008

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title = "Contrast-enhanced cardiac MRI before coronary artery bypass surgery: Impact of myocardial scar extent on bypass flow",

abstract = "The aim of the study was to relate the extent of myocardial late gadolinium enhancement (LGE) in cardiac MRI to intraoperative graft flow in patients undergoing coronary artery bypass graft (CABG) surgery. Thirty-three CAD patients underwent LGE MRI before surgery using an inversion-recovery GRE sequence (turboFLASH). Intraoperative graft flow in Doppler ultrasonography was compared with the scar extent in each coronary vessel territory. One hundred and fourteen grafts were established supplying 86 of the 99 vessel territories. A significant negative correlation was found between scar extent and graft flow (r=-0.4, p<0.0001). Flow in grafts to territories with no or small subendocardial scar was significantly higher than in grafts to territories with broad nontransmural or transmural scar (75±39 vs. 38±26 cc min-1; p<0.0001). In summary, the extent of myocardial scar as defined by contrast-enhanced MRI predicts coronary bypass graft flow. Beyond the probability of functional recovery, preoperative MRI might add value to surgery planning by predicting midterm bypass graft patency.",

author = "Peter Hunold and Parwis Massoudy and Claudia Boehm and Thomas Schlosser and Kai Nassenstein and Stephan Knipp and Holger Eggebrecht and Matthias Thielmann and Raimund Erbel and Heinz Jakob and J{\"o}rg Barkhausen",

year = "2008",

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doi = "10.1007/s00330-008-1066-y",

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TY - JOUR

T1 - Contrast-enhanced cardiac MRI before coronary artery bypass surgery

T2 - Impact of myocardial scar extent on bypass flow

AU - Hunold, Peter

AU - Massoudy, Parwis

AU - Boehm, Claudia

AU - Schlosser, Thomas

AU - Nassenstein, Kai

AU - Knipp, Stephan

AU - Eggebrecht, Holger

AU - Thielmann, Matthias

AU - Erbel, Raimund

AU - Jakob, Heinz

AU - Barkhausen, Jörg

PY - 2008/6/26

Y1 - 2008/6/26

N2 - The aim of the study was to relate the extent of myocardial late gadolinium enhancement (LGE) in cardiac MRI to intraoperative graft flow in patients undergoing coronary artery bypass graft (CABG) surgery. Thirty-three CAD patients underwent LGE MRI before surgery using an inversion-recovery GRE sequence (turboFLASH). Intraoperative graft flow in Doppler ultrasonography was compared with the scar extent in each coronary vessel territory. One hundred and fourteen grafts were established supplying 86 of the 99 vessel territories. A significant negative correlation was found between scar extent and graft flow (r=-0.4, p<0.0001). Flow in grafts to territories with no or small subendocardial scar was significantly higher than in grafts to territories with broad nontransmural or transmural scar (75±39 vs. 38±26 cc min-1; p<0.0001). In summary, the extent of myocardial scar as defined by contrast-enhanced MRI predicts coronary bypass graft flow. Beyond the probability of functional recovery, preoperative MRI might add value to surgery planning by predicting midterm bypass graft patency.

AB - The aim of the study was to relate the extent of myocardial late gadolinium enhancement (LGE) in cardiac MRI to intraoperative graft flow in patients undergoing coronary artery bypass graft (CABG) surgery. Thirty-three CAD patients underwent LGE MRI before surgery using an inversion-recovery GRE sequence (turboFLASH). Intraoperative graft flow in Doppler ultrasonography was compared with the scar extent in each coronary vessel territory. One hundred and fourteen grafts were established supplying 86 of the 99 vessel territories. A significant negative correlation was found between scar extent and graft flow (r=-0.4, p<0.0001). Flow in grafts to territories with no or small subendocardial scar was significantly higher than in grafts to territories with broad nontransmural or transmural scar (75±39 vs. 38±26 cc min-1; p<0.0001). In summary, the extent of myocardial scar as defined by contrast-enhanced MRI predicts coronary bypass graft flow. Beyond the probability of functional recovery, preoperative MRI might add value to surgery planning by predicting midterm bypass graft patency.

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U2 - 10.1007/s00330-008-1066-y

DO - 10.1007/s00330-008-1066-y

M3 - Journal articles

C2 - 18581115

AN - SCOPUS:56349169312

SN - 0938-7994

VL - 18

SP - 2756

EP - 2764

JO - European Radiology

JF - European Radiology

IS - 12

ER -

Contrast-enhanced cardiac MRI before coronary artery bypass surgery: Impact of myocardial scar extent on bypass flow

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