Abstract
Complex dystonias are defined as dystonias that are accompanied by neurologic or systemic manifestations beyond movement disorders. Many syndromes or diseases can present with complex dystonia, either as the cardinal sign or as part of a multi-systemic manifestation. Complex dystonia often gradually develops in the disease course, but can also be present from the outset. If available, the diagnostic workup, disease-specific treatment, and management of patients with complex dystonias require a multi-disciplinary approach. This article summarizes current knowledge on complex dystonias with a particular view of recent developments with respect to advances in diagnosis and management, including causative treatments.
| Original language | English |
|---|---|
| Journal | Journal of Neural Transmission |
| ISSN | 0300-9564 |
| DOIs | |
| Publication status | Published - 13.11.2020 |
Funding
Open Access funding enabled and organized by Projekt DEAL. This work was supported by the DFG (SFB 936, project C5) and the Else Kröner—Fresenius Foundation (2018_A55). R.H., A.W., T.B., and A.M. are members of the European Reference Network for Rare Neurological Diseases—Project ID No 739510. R.H. is supported by the section of medicine of the University of Lübeck (CS08-2020). Acknowledgements This work was supported by the DFG (SFB 936, project C5) and the Else Kröner—Fresenius Foundation (2018_A55). R.H., A.W., T.B., and A.M. are members of the European Reference Network for Rare Neurological Diseases—Project ID No 739510.
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)
