Complete cDNA sequence, expression, alternative splicing, and genomic organization of the mouse Nfat5 gene

A. Dalski; A. Hebinck; H. Winking; U. Butzmann; E. Schwinger; Ch Zühlkea

doi:10.1159/000066604

Complete cDNA sequence, expression, alternative splicing, and genomic organization of the mouse Nfat5 gene

A. Dalski, A. Hebinck, H. Winking, U. Butzmann, E. Schwinger, Ch Zühlkea^*

^*Corresponding author for this work

Institute of Biology

Harvard University

1 Citation (Scopus)

Abstract

Members of the NFAT (nuclear factors of activated T cells) gene family have been investigated in numerous organisms, including man and mouse. All NFATs may be synthesized in several isoforms differing in amino or carboxy termini due to 5′ and 3′ alternative splicing of the corresponding mRNA. Recently, we mapped the murine Nfat5 gene to chromosome 8D. In the present paper we describe for the first time the complete sequence and primary structure of murine Nfat5, two new spliced isoforms, and the expression of murine Nfat5 in embryonic and adult mouse tissues.

Original language	English
Journal	Cytogenetic and Genome Research
Volume	97
Issue number	3-4
Pages (from-to)	179-182
Number of pages	4
ISSN	1424-8581
DOIs	https://doi.org/10.1159/000066604
Publication status	Published - 01.12.2002

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AU - Dalski, A.

AU - Hebinck, A.

AU - Winking, H.

AU - Butzmann, U.

AU - Schwinger, E.

AU - Zühlkea, Ch

PY - 2002/12/1

Y1 - 2002/12/1

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AB - Members of the NFAT (nuclear factors of activated T cells) gene family have been investigated in numerous organisms, including man and mouse. All NFATs may be synthesized in several isoforms differing in amino or carboxy termini due to 5′ and 3′ alternative splicing of the corresponding mRNA. Recently, we mapped the murine Nfat5 gene to chromosome 8D. In the present paper we describe for the first time the complete sequence and primary structure of murine Nfat5, two new spliced isoforms, and the expression of murine Nfat5 in embryonic and adult mouse tissues.

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JO - Cytogenetic and Genome Research

JF - Cytogenetic and Genome Research

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ER -

Complete cDNA sequence, expression, alternative splicing, and genomic organization of the mouse Nfat5 gene

Abstract

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