Comparison of Three Survival Scores in a Series of Patients ≥80 Years of Age Irradiated for Bone Metastases

Dirk Rades*, Cansu Delikanli, Steven E. Schild, Charlotte Kristiansen, Soren Tvilsted, Stefan Janssen

*Corresponding author for this work
1 Citation (Scopus)


Background/Aim: Very elderly patients irradiated for bone metastases likely benefit from individualized treatments. A specific survival score was created for this group and compared to existing instruments. Patients and Methods: Ninety-six patients aged 80+ irradiated for bone metastases were retrospectively evaluated. Dose-fractionation regimen plus twelve characteristics were evaluated for survival. Results: In the Cox regression model, performance status and tumor type were significant and used for the score, which included three groups (5-7, 8-12, and 14 points) with 6-month survival rates of 15%, 52%, and 90%. Positive predictive values (PPVs) regarding death ≤6 months were 85% (new score), 100% (previous 65+ score), and 84% (previous score for any age). The new instrument and the 65+ score were also very accurate regarding survival. Since PPV regarding death was calculated from only four patients for the 65+ score, this PPV may be less conclusive than that for the new instrument. Conclusion: The new score appears useful for patients aged 80+ irradiated for bone metastases.

Original languageEnglish
JournalAnticancer Research
Issue number2
Pages (from-to)801-807
Number of pages7
Publication statusPublished - 02.2023

Research Areas and Centers

  • Research Area: Luebeck Integrated Oncology Network (LION)
  • Centers: University Cancer Center Schleswig-Holstein (UCCSH)


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