Cohort Profile: The Berlin aging study II (BASE-II)

Lars Bertram, Anke Böckenhoff, Ilja Demuth, Sandra Düzel, Rahel Eckardt, Shu Chen Li, Ulman Lindenberger, Graham Pawelec, Thomas Siedler, Gert G. Wagner, Elisabeth Steinhagen-Thiessen*

*Corresponding author for this work
    47 Citations (Scopus)

    Abstract

    Similar to other industrialized countries, Germany's population is ageing. Whereas some people enjoy good physical and cognitive health into old age, others suffer from a multitude of age-related disorders and impairments which reduce life expectancy and affect quality of life. To identify and characterize the factors associated with 'healthy' vs. 'unhealthy' ageing, we have launched the Berlin Aging Study II (BASE-II), a multidisciplinary and multi-institutional project that ascertains a large number of ageing-related variables from a wide range of different functional domains. Phenotypic assessments include factors related to geriatrics and internal medicine, immunology, genetics, psychology, sociology and economics. Baseline recruitment of the BASE-II cohort was recently completed and has led to the sampling of 1600 older adults (age range 60-80 years), as well as 600 younger adults (20-35 years) serving as the basic population for in-depth analyses. BASE-II data are linked to the German Socio-Economic Panel Study (SOEP), a long-running panel survey representative of the German population, to estimate sample selectivity. A major goal of BASE-II is to facilitate collaboration with other research groups by freely sharing relevant phenotypic and genotypic data with qualified outside investigators.

    Original languageEnglish
    Article numberdyt018
    JournalInternational Journal of Epidemiology
    Volume43
    Issue number3
    Pages (from-to)703-712
    Number of pages10
    ISSN0300-5771
    DOIs
    Publication statusPublished - 01.01.2014

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