Circadian regulation of endocrine systems

Anne Marie Neumann; Cosima Xenia Schmidt; Ruth Merle Brockmann; Henrik Oster

doi:10.1016/j.autneu.2018.10.001

Circadian regulation of endocrine systems

Anne Marie Neumann, Cosima Xenia Schmidt, Ruth Merle Brockmann, Henrik Oster^*

^*Corresponding author for this work

66 Citations (Scopus)

Abstract

Hormones are major systemic regulators of homeostatic functions. Not surprisingly, most endocrine signals show some extent of variation across the day. This holds true for the three major hormonal axes of the body originating from the hypothalamus, relayed by the pituitary and terminating in the adrenal (HPA axis), the thyroid (HPT axis), and the gonads (HPG axis), respectively. The rhythmicity of endocrine axis formation has important functions for the maintenance of homeostasis and stabilizes physiological functions against external perturbations. In some cases, such as cortisol, hormonal signals are themselves implicated in circadian regulation and, thus, endocrine disruption may affect the function of the circadian clock network to alter further downstream processes.

Original language	English
Journal	Autonomic Neuroscience: Basic and Clinical
Volume	216
Pages (from-to)	1-8
Number of pages	8
ISSN	1566-0702
DOIs	https://doi.org/10.1016/j.autneu.2018.10.001
Publication status	Published - 01.01.2019

Funding

This work was supported by grants of the German Research Foundation ( GRK1957 ) and the German Volkswagen Foundation (Lichtenberg program professorship).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 8 Decent Work and Economic Growth
SDG 10 Reduced Inequalities

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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10.1016/j.autneu.2018.10.001

Cite this

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AU - Oster, Henrik

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JO - Autonomic Neuroscience: Basic and Clinical

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Circadian regulation of endocrine systems

Abstract

Funding

UN SDGs

Research Areas and Centers

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