Cholesterol homeostasis: Another twist on eSCAPe from the ER


It is essential for mammalian cells to tightly regulate cholesterol content in their membranes. To this aim, they use a variety of feedback mechanisms that control cholesterol biosynthesis, storage as esters, and import from and export to circulating lipoproteins. The control of cellular cholesterol synthesis involves a fascinating series of regulated membrane-trafficking events. Recently, more details of the underlying mechanism have emerged.
Original languageEnglish
JournalTrends in Cell Biology
Issue number11
Pages (from-to)500
Number of pages1
Publication statusPublished - 01.11.2002

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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