Characterization of patients with psoriatic arthritis in dermatologic and rheumatologic care: analysis of two registries

Matthias Augustin, Lisa Lindner, Laura Kühl, Anja Weiss, Stephan Jeff Rustenbach, Brigitte Stephan, Martin Feuchtenberger, Ulrich Mrowietz, Diamant Thaçi, Petra Staubach, Xenofon Baraliakos, Anja Strangfeld, Ralph von Kiedrowski, Frank Behrens, Anne Constanze Regierer*

*Corresponding author for this work
1 Citation (Scopus)

Abstract

Background and objective: Psoriatic arthritis (PsA) is a chronic systemic inflammatory disease affecting the musculoskeletal system, skin and nails. The aim is to characterize sociodemographic and clinical patient profiles documented in dermatologic and rheumatologic care. Patients and Methods: Data of 704 patients with PsA from the dermatological Psoriasis Registry PsoBest (PB) and 1066 patients from the rheumatological disease registry RABBIT-SpA (RS) were analyzed. Comparable anamnestic and clinical variables were identified and descriptively analyzed. Results: The mean age was 51.7 years in PB and 51.9 in RS. Disease duration of psoriasis was longer, mean cutaneous severity was higher in PB. However, more patients in RS vs. PB had tender joints and swollen joints. Mean Dermatology Life Quality Index was higher in PB and mean Health Assessment Questionnaire in RS. Patient reported global disease activity and pain were lower in PB. IL-23 inhibitors were used more frequently in PB, and TNF inhibitors in RS. Conclusions: Clinical specialization was associated with different clinical and treatment patterns of PsA. This may indicate a selection by dominant manifestation of psoriatic disease and potentially by effects of health care access. Psoriatic arthritis should be treated in a multidisciplinary approach considering all facets of this complex disease.

Original languageEnglish
JournalJDDG - Journal of the German Society of Dermatology
Volume21
Issue number10
Pages (from-to)1170-1176
Number of pages7
ISSN1610-0379
DOIs
Publication statusPublished - 10.2023

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)
  • Centers: Center for Research on Inflammation of the Skin (CRIS)

DFG Research Classification Scheme

  • 205-19 Dermatology
  • 205-18 Rheumatology
  • 204-05 Immunology

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