Changes in direct current (DC) potentials and infra-slow EEG oscillations at the onset of the luteinizing hormone (LH) pulse

Lisa Marshall*, Matthias Mölle, Horst L. Fehm, Jan Born

*Corresponding author for this work
12 Citations (Scopus)

Abstract

An essential function of the neuroendocrine system lies in the coordination of hypothalamo-pituitary secretory activity with neocortical neuronal activity. Cortical direct current (DC) potential shifts and EEG were monitored in conjunction with the circulating concentration of luteinizing hormone (LH) in humans while asleep to assess a hypothalamic-neocortical interaction. The onset of an LH pulse was accompanied (i) at frontocortical locations by a transient positive DC potential shift of =3min duration and peak amplitude 50 μV; (ii) at frontal and central locations by an increase in power of infra-slow EEG oscillations for periodicities between 64 and 320 s. Results uniquely demonstrate a coupling of hypothalamo-pituitary activity with regulation of neocortical excitability.

Original languageEnglish
JournalEuropean Journal of Neuroscience
Volume12
Issue number11
Pages (from-to)3935-3943
Number of pages9
ISSN0953-816X
DOIs
Publication statusPublished - 2000

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