Cartilage tissue engineering using resorbable scaffolds

Nicole Rotter*, Markus Bücheler, Andreas Haisch, Barbara Wollenberg, Stephan Lang

*Corresponding author for this work
33 Citations (Scopus)


Cartilage tissue engineering holds considerable promise for orthopaedic and reconstructive head and neck surgery. With an increasingly ageing population, the number of patients affected by arthritis and recurrent joint pain is constantly growing, along with the associated socio-economic costs. In head and neck surgery reconstructive procedures gain increasing importance in multimodal tumour therapies. These procedures require the harvesting of large amounts of donor tissue, which causes significant donor site morbidity. Therefore, in vitro-engineered cartilage may provide for a cost-effective and clinically valuable medical need. This article presents an overview of the clinical background as well as considerations for engineered cartilage in the head and neck, and provides examples of cartilage tissue engineering based on various scaffolds.

Original languageEnglish
JournalJournal of tissue engineering and regenerative medicine
Issue number6
Pages (from-to)411-416
Number of pages6
Publication statusPublished - 09.2007


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