Bullöse autoimmunerkrankungen des kindesalters

Translated title of the contribution: Blistering autoimmune diseases of childhood

M. Goebeler, D. Zillikens

4 Citations (Scopus)


Autoimmune blistering skin diseases are exceedingly rare in children. In most cases, they are characterized by circulating autoantibodies directed against adhesion structures of the skin which subsequently induce blistering at the dermoepidermal junction or intraepidermally. The most frequent paediatric immunobullous disease is linear IgA dermatosis; all others such as pemphigoid, epidermolysis bullosa acquisita, dermatitis herpetiformis and pemphigus are less common than in adults. In children, mucous membranes are involved more frequently. Recent advances in the identification of the autoantigens have improved diagnostic approach and therapeutic management of blistering diseases. In most cases, treatment requires systemic immuno-suppression. With respect to the chronic course of the diseases and potential complications of treatment, cooperation between dermatologists and paediatricians seems advisable.

Translated title of the contributionBlistering autoimmune diseases of childhood
Original languageGerman
Issue number1
Pages (from-to)14-24
Number of pages11
Publication statusPublished - 01.01.2003


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