Brain Shift and Updated Intraoperative Navigation with Intraoperative MRI

Arya Nabavi, Heinz Handels


Image-guided navigation provides a valuable adjunct to neurosurgical procedures. However, since the brain is not a rigid body, intraoperative changes, summarized as “brain shift”, represent a major practical and theoretical challenge. Intraoperative imaging, in particular intraoperative MRI to update information on computer-assisted navigation systems, solves the practical issue. However, capturing, characterizing and modelling brain deformation have opened interesting research avenues, which may lead to a more thorough understanding of the biomechanical properties of the brain. Potential applications go beyond surgical simulation. Obtaining data on the viscoelastic properties of the brain may yield valuable information in regard to physiological (e.g. ageing) as well as pathological conditions (reactions to traumatic brain injuries as well as degenerative diseases).

In this chapter, we portray the development of “brain shift” characterization and potential future directions, as well as the development and practical application of updated surgical navigation with intraoperative MRI.
Original languageEnglish
Title of host publicationIntraopertive Imaging and Image-Guided Therapy
EditorsFerenc. A. Jolesz
Number of pages11
PublisherSpringer Verlag
Publication date25.11.2013
Publication statusPublished - 25.11.2013


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