Grand-average ERPs from left and right temporoparietal sites (P7/P8) showing a marked increase of N1 amplitude for group H. Mean amplitude (160–180ms) at this electrode pair showed an overall group difference (F(2,21)1⁄46.98; Po0.005) with post hoc tests (Scheffe ́) indicating differences between group H and controls (Po0.01), group H and group L (Po0.01), but no difference between group L and controls. (b) Source analysis (LORETA) for the grand average showed a prominent left temporoparietal source at 152 ms for group H subjects corresponding to Brodmann areas 19/37/39. Voxels in the region marked in black showed activity higher than 0.01mA/mm2. (c) A statistical comparison of the individual source solutions (LORETA, time window 140–180ms) of group H and control subjects revealed group differences in medial frontal and lateral temporo- occipital regions. The darker zones (encircled) represent those voxels for which t-values exceeded the threshold of significance (corrected for multiple comparisons). For more information on this topic, please see the article by Dietrich et al on pages 519–520.
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)