TY - JOUR
T1 - Brain potential amplitude varies as a function of Borna disease virus-specific immune complexes in obsessive-compulsive disorder
AU - Dietrich, D. E.
AU - Zhang, Y.
AU - Bode, L.
AU - Münte, T. F.
AU - Hauser, U.
AU - Schmorl, P.
AU - Richter-Witte, C.
AU - Gödecke-Koch, T.
AU - Feutl, S.
AU - Schramm, J.
AU - Ludwig, H.
AU - Johannes, S.
AU - Emrich, H. M.
PY - 2005/6/1
Y1 - 2005/6/1
N2 - Grand-average ERPs from left and right temporoparietal sites (P7/P8) showing a marked increase of N1 amplitude for group H. Mean amplitude (160–180ms) at this electrode pair showed an overall group difference (F(2,21)1⁄46.98; Po0.005) with post hoc tests (Scheffe ́) indicating differences between group H and controls (Po0.01), group H and group L (Po0.01), but no difference between group L and controls. (b) Source analysis (LORETA) for the grand average showed a prominent left temporoparietal source at 152 ms for group H subjects corresponding to Brodmann areas 19/37/39. Voxels in the region marked in black showed activity higher than 0.01mA/mm2. (c) A statistical comparison of the individual source solutions (LORETA, time window 140–180ms) of group H and control subjects revealed group differences in medial frontal and lateral temporo- occipital regions. The darker zones (encircled) represent those voxels for which t-values exceeded the threshold of significance (corrected for multiple comparisons). For more information on this topic, please see the article by Dietrich et al on pages 519–520.
AB - Grand-average ERPs from left and right temporoparietal sites (P7/P8) showing a marked increase of N1 amplitude for group H. Mean amplitude (160–180ms) at this electrode pair showed an overall group difference (F(2,21)1⁄46.98; Po0.005) with post hoc tests (Scheffe ́) indicating differences between group H and controls (Po0.01), group H and group L (Po0.01), but no difference between group L and controls. (b) Source analysis (LORETA) for the grand average showed a prominent left temporoparietal source at 152 ms for group H subjects corresponding to Brodmann areas 19/37/39. Voxels in the region marked in black showed activity higher than 0.01mA/mm2. (c) A statistical comparison of the individual source solutions (LORETA, time window 140–180ms) of group H and control subjects revealed group differences in medial frontal and lateral temporo- occipital regions. The darker zones (encircled) represent those voxels for which t-values exceeded the threshold of significance (corrected for multiple comparisons). For more information on this topic, please see the article by Dietrich et al on pages 519–520.
UR - http://www.scopus.com/inward/record.url?scp=21244483480&partnerID=8YFLogxK
U2 - 10.1038/sj.mp.4001688
DO - 10.1038/sj.mp.4001688
M3 - Journal articles
C2 - 15668719
AN - SCOPUS:21244483480
SN - 1359-4184
VL - 10
JO - Molecular Psychiatry
JF - Molecular Psychiatry
IS - 6
ER -