For localized muscle-invasive bladder cancer, radical cystectomy has been widely considered as the standard treatment. However, numerous phase II studies with concurrent chemoradiotherapy have demonstrated survival rates identical to surgical series with 70–80 % bladder preservation in long-term survivors. Chemoradiation is the standard of care for organ preservation, and radiotherapy alone might offer effective palliation of symptoms, such as pain and hematuria, even in patients with very advanced disease. The principles of target volume delineation and treatment planning are outlined in this chapter.
|Title of host publication
|Target Volume Definition in Radiation Oncology
|Number of pages
|Springer Berlin Heidelberg
|Published - 01.01.2015