Bildgebende diagnostik beim CUP-syndrom: Unter besonderer berücksichtigung der positronenemissionstomographie

Translated title of the contribution: Diagnostic imaging for cancer of unknown primary (CUP syndrome)

D. Rades*

*Corresponding author for this work


The initial stage of CUP syndrome is either localized or disseminated. In cases of dissemination, the treatment intention is palliative. If the disease is still localized, the therapeutic approach can be considered potentially curative. In patients with localized disease, diagnostic imaging is particularly important because detection of the primary tumor may lead to improved survival. If the dissemination of disease is detected early, further diagnostic procedures can be avoided. The results of fluorodeoxyglucose positron emission tomography (FDG-PET) frequently have a significant impact on the therapeutic strategy. FDG-PET is superior to other diagnostic procedures regarding the detection of both the primary tumor and dissemination. FDG-PET should be performed early to avoid further diagnostic procedures that may cause unnecessary discomfort for the patient. It may well be that the results of FDG-PET can be further improved with the use of PET-computed tomography.

Translated title of the contributionDiagnostic imaging for cancer of unknown primary (CUP syndrome)
Original languageGerman
Issue number9
Pages (from-to)879-891
Number of pages13
Publication statusPublished - 09.2008


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