Benign neonatal hemangiomatosis in a pre-term infant

Benign neonatal hemangiomatosis (BNH) is a condition of multiple neonatal strawberry hemangiomas limited to the skin. Characteristically, a rapid proliferative growth phase is followed by a prolonged involutional phase. Regression of cutaneous lesions usually starts in the fourth month, but variations until complete involution are high for individial lesions. Disseminated neonatal hemangiomatosis (DNH) represents a serious multisystemic disorder with hemangiomas in different organs and the skin. Early evaluation of the patients and treatment of visceral hemangiomas is of crucial importance. While solitary hemangiomas have been reported to occur more commonly in pre-term infants, prematurity has rarely been described in the literature as being associated with BNH.