Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Christoph Helmchen; Stefan Gottschalk; Thurid Sander; Peter Trillenberg; Holger Rambold; Andreas Sprenger

doi:10.1007/s00415-006-0448-9

Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Christoph Helmchen^*, Stefan Gottschalk, Thurid Sander, Peter Trillenberg, Holger Rambold, Andreas Sprenger

^*Corresponding author for this work

22 Citations (Scopus)

Abstract

Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

Original language	English
Journal	Journal of Neurology
Volume	254
Issue number	8
Pages (from-to)	1126-1128
Number of pages	3
ISSN	0340-5354
DOIs	https://doi.org/10.1007/s00415-006-0448-9
Publication status	Published - 01.08.2007

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s00415-006-0448-9

Cite this

@article{35d7a1c0da374bd189da05e7a9975366,

title = "Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]",

abstract = "Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.",

author = "Christoph Helmchen and Stefan Gottschalk and Thurid Sander and Peter Trillenberg and Holger Rambold and Andreas Sprenger",

year = "2007",

month = aug,

day = "1",

doi = "10.1007/s00415-006-0448-9",

language = "English",

volume = "254",

pages = "1126--1128",

journal = "Journal of Neurology",

issn = "0340-5354",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "8",

}

TY - JOUR

T1 - Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

AU - Helmchen, Christoph

AU - Gottschalk, Stefan

AU - Sander, Thurid

AU - Trillenberg, Peter

AU - Rambold, Holger

AU - Sprenger, Andreas

PY - 2007/8/1

Y1 - 2007/8/1

N2 - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

AB - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

UR - https://www.scopus.com/pages/publications/34548408723

U2 - 10.1007/s00415-006-0448-9

DO - 10.1007/s00415-006-0448-9

M3 - Letters

C2 - 17410325

AN - SCOPUS:34548408723

SN - 0340-5354

VL - 254

SP - 1126

EP - 1128

JO - Journal of Neurology

JF - Journal of Neurology

IS - 8

ER -

Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Abstract

Research Areas and Centers

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this