Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Christoph Helmchen; Stefan Gottschalk; Thurid Sander; Peter Trillenberg; Holger Rambold; Andreas Sprenger

doi:10.1007/s00415-006-0448-9

Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Christoph Helmchen^*, Stefan Gottschalk, Thurid Sander, Peter Trillenberg, Holger Rambold, Andreas Sprenger

^*Corresponding author for this work

23 Citations (Scopus)

Abstract

Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

Original language	English
Journal	Journal of Neurology
Volume	254
Issue number	8
Pages (from-to)	1126-1128
Number of pages	3
ISSN	0340-5354
DOIs	https://doi.org/10.1007/s00415-006-0448-9
Publication status	Published - 01.08.2007

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Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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title = "Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]",

abstract = "Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.",

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T1 - Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

AU - Helmchen, Christoph

AU - Gottschalk, Stefan

AU - Sander, Thurid

AU - Trillenberg, Peter

AU - Rambold, Holger

AU - Sprenger, Andreas

PY - 2007/8/1

Y1 - 2007/8/1

N2 - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

AB - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.

UR - https://www.scopus.com/pages/publications/34548408723

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DO - 10.1007/s00415-006-0448-9

M3 - Letters

C2 - 17410325

AN - SCOPUS:34548408723

SN - 0340-5354

VL - 254

SP - 1126

EP - 1128

JO - Journal of Neurology

JF - Journal of Neurology

IS - 8

ER -

Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]

Abstract

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