TY - JOUR
T1 - Beneficial effects of 3,4-diaminopyridine on positioning downbeat nystagmus in a circumscribed uvulo-nodular lesion [6]
AU - Helmchen, Christoph
AU - Gottschalk, Stefan
AU - Sander, Thurid
AU - Trillenberg, Peter
AU - Rambold, Holger
AU - Sprenger, Andreas
PY - 2007/8/1
Y1 - 2007/8/1
N2 - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.
AB - Sirs: Central positioning downbeat nystagmus (pDBN) presents with transient nystagmus in supine or the head hanging position in the absence of DBN in the head erect position. In contrast to central positional downbeat nystagmus, pDBN requires rapid head posi- tioning manoeuvres to be elicited. The pathomechanism and therapy of central pDBN is not yet known and circumscribed lesions are missing so far [1, 2]. We examined the effect of 3,4-diaminopyridine (DAP) [3, 4] on the oculomotor behavior of a patient with pDBN.
UR - http://www.scopus.com/inward/record.url?scp=34548408723&partnerID=8YFLogxK
U2 - 10.1007/s00415-006-0448-9
DO - 10.1007/s00415-006-0448-9
M3 - Letters
C2 - 17410325
AN - SCOPUS:34548408723
SN - 0340-5354
VL - 254
SP - 1126
EP - 1128
JO - Journal of Neurology
JF - Journal of Neurology
IS - 8
ER -