Based on a retrospective multicenter autopsy study on medical malpractice claims cases concerning emergency physicians and ambulance officers will be addressed. Malpractice claims against emergency physicians are not as frequent as against emergency service doctors. Claims are mainly due to wrong diagnosis and treatment, missed diagnosis or missing hospital admission. Especially myocardial infarctions are misdiagnosed not seldom. The rate of confirmed cases of medical malpractice is for emergency physicians with 10.2% behind other medical disciplines. Ambulance officers are mainly confronted with claims of omitted admission to hospitals or information of an emergency physician. Malpractice claims with approved causality for death are very rare. Autopsy findings are in most cases in favor of doctors. Therefore in suspicious cases a medico-legal autopsy should be strived for by qualifying the manner of death as unnatural.