TY - JOUR
T1 - Balloon Eustachian Tuboplasty (BET) in Children: A Retrospective Multicenter Analysis
AU - Tisch, Matthias
AU - Maier, Susanne
AU - Preyer, Serena
AU - Kourtidis, Savvas
AU - Lehnerdt, Goetz
AU - Winterhoff, Sebastian
AU - Dalchow, Carsten V.
AU - Mueller-Jenckel, Friederike
AU - Sudhoff, Holger H.
AU - Schröder, Stefanie
AU - Koitschev, Assen
AU - Amrhein, Peter
AU - Bruchhage, Karl Ludwig
AU - Leichtle, Anke
AU - Güldner, Christian
AU - Grulich-Henn, Juergen
AU - Jensen, Katrin
AU - Pohl, Moritz
AU - Plinkert, Peter K.
AU - Euteneuer, Sara
N1 - Funding Information:
This research project was carried out without any specific internal or external funding support. M.T., S.P., S.K., S.W., G.L., C.V.D., H.H.S., S.S., P.A., K.L.B., A.L., C.G., J.G.H., and S.E. received reimbursements for travel expenses from the manufarcurer of the Eustachian tube balloon utilized in this study (Spiggle & Theis Medizintechnik, Overath, Germany). C.V.D., H.H.S., and S.E. received financial support for holding symposia from Spiggle & Theis Medizintechnik. In addition, C.V.D. received consulting fees, S.S. financial support for another clinical study, and H.H.S. grant support form Spiggle & Theis Medizintechnik. All other authors have indicated that they have no financial competing interests, or other relationships that might lead to bias relevant to this manuscript.
Publisher Copyright:
© 2020 Lippincott Williams and Wilkins. All rights reserved.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Objective:Generation of pilot data for planning of prospective BET-studies for treatment of dilatory Eustachian tube (ET) dysfunction in children.Study Design:Retrospective multicenter analysis.Setting:Nine ENT departments at tertiary care teaching hospitals.Patients:4-12-year-old children with chronic otitis media with effusion (COME) for more than 3 months or more than 3 episodes of acute otitis media during the last year, having failed standard surgical therapy at least once.Intervention:BET with or without paracentesis, ventilation tube insertion, or tympanoplasty.Main outcome measures:Tympanic membrane appearance, tympanometry, and hearing threshold.Results:Two hundred ninety-nine ETs of 167 children were treated. Mean age was 9.1 years (95% confidence interval [95% CI]: 8.7-9.4 yr). In 249 ears (83.3%), COME and/or retraction of the tympanic membrane were the indication for BET. Median hearing threshold was 20 dB HL (95% CI: 0-46 dB). One hundred fifty-five ears (51.8%, 95% CI: 46.1-57.4%) showed a tympanogram type B. Treatment consisted of BET without other interventions ("BET-only") in 70 children, 128 ears. Median length of follow-up for 158 (94.6%) children was 2.6 months (95% CI: 0.3-16.1 mo). After treatment, the tympanic membrane appeared normal in 196 ears (65.6%, 95% CI: 60.0-70.8%, p < 0.001). Median hearing threshold improved to 10 dB HL (95% CI: 0-45 dB, p < 0.001). Tympanograms shifted toward type A and C (type A: 39.1%, 95% CI: 33.7-44.7, p < 0.001). These improvements were also observed in subgroup analyses of "BET-only" treatment and the indication of "COME" respectively.Conclusion:BET is improving a variety of dilatory ET dysfunction-related ear diseases in children. This study provides detailed data for design and planning of prospective studies on BET in children.
AB - Objective:Generation of pilot data for planning of prospective BET-studies for treatment of dilatory Eustachian tube (ET) dysfunction in children.Study Design:Retrospective multicenter analysis.Setting:Nine ENT departments at tertiary care teaching hospitals.Patients:4-12-year-old children with chronic otitis media with effusion (COME) for more than 3 months or more than 3 episodes of acute otitis media during the last year, having failed standard surgical therapy at least once.Intervention:BET with or without paracentesis, ventilation tube insertion, or tympanoplasty.Main outcome measures:Tympanic membrane appearance, tympanometry, and hearing threshold.Results:Two hundred ninety-nine ETs of 167 children were treated. Mean age was 9.1 years (95% confidence interval [95% CI]: 8.7-9.4 yr). In 249 ears (83.3%), COME and/or retraction of the tympanic membrane were the indication for BET. Median hearing threshold was 20 dB HL (95% CI: 0-46 dB). One hundred fifty-five ears (51.8%, 95% CI: 46.1-57.4%) showed a tympanogram type B. Treatment consisted of BET without other interventions ("BET-only") in 70 children, 128 ears. Median length of follow-up for 158 (94.6%) children was 2.6 months (95% CI: 0.3-16.1 mo). After treatment, the tympanic membrane appeared normal in 196 ears (65.6%, 95% CI: 60.0-70.8%, p < 0.001). Median hearing threshold improved to 10 dB HL (95% CI: 0-45 dB, p < 0.001). Tympanograms shifted toward type A and C (type A: 39.1%, 95% CI: 33.7-44.7, p < 0.001). These improvements were also observed in subgroup analyses of "BET-only" treatment and the indication of "COME" respectively.Conclusion:BET is improving a variety of dilatory ET dysfunction-related ear diseases in children. This study provides detailed data for design and planning of prospective studies on BET in children.
UR - http://www.scopus.com/inward/record.url?scp=85088485261&partnerID=8YFLogxK
U2 - 10.1097/MAO.0000000000002789
DO - 10.1097/MAO.0000000000002789
M3 - Journal articles
C2 - 32658110
AN - SCOPUS:85088485261
SN - 1531-7129
VL - 41
SP - e921-e933
JO - Otology and Neurotology
JF - Otology and Neurotology
IS - 7
ER -
