TY - JOUR
T1 - Automatic aspects of response selection remain unchanged during high-dose alcohol intoxication
AU - Stock, Ann Kathrin
AU - Bensmann, Wiebke
AU - Zink, Nicolas
AU - Münchau, Alexander
AU - Beste, Christian
N1 - Funding Information:
This work was supported by the Deutsche Forschungsgemeinschaft (DFG) TRR 265 B07 and FOR 2698.
Publisher Copyright:
© 2019 Society for the Study of Addiction
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/12/10
Y1 - 2019/12/10
N2 - Regular binge-drinking increases the risk of developing alcohol use disorder (AUD) and induces similar acute effects on behavioral control, particularly in case of response selection conflicts. No such effects have been reported for automatic/bottom-up response selection, even though AUD alters automaticity. However, it has never been reliably tested whether this domain is truly unchanged during high-dose alcohol intoxication. To investigate this question with the help of Bayesian analyses, we subjected n=31 young healthy male participants to a within-subject design, where each participant was tested twice in a counter-balanced order (ie, once sober and once intoxicated at 1.1‰). On each appointment, the participants performed the S-R paradigm, which assesses automatic stimulus-response (S-R) binding within the framework of the theory of event coding (TEC). In short, the TEC states that stimulus features and responses become encoded in an event file when they occur simultaneously. These event files will be reactivated by any matching stimulus feature, thus facilitating the encoded response (and hampering different responses). Alcohol led to a general decrease in behavioral performance, as demonstrated by significant main effects of intoxication status on accuracy and response times (all P ≤.009). We also reproduced typical task effects, but did not find any significant interactions with the intoxication factor (all P ≥.099). The latter was further substantiated by Bayesian analyses providing positive to strong evidence for the null hypothesis. Taken together, our results demonstrate that even high-dose alcohol intoxication does not impair automatic response selection/S-R associations.
AB - Regular binge-drinking increases the risk of developing alcohol use disorder (AUD) and induces similar acute effects on behavioral control, particularly in case of response selection conflicts. No such effects have been reported for automatic/bottom-up response selection, even though AUD alters automaticity. However, it has never been reliably tested whether this domain is truly unchanged during high-dose alcohol intoxication. To investigate this question with the help of Bayesian analyses, we subjected n=31 young healthy male participants to a within-subject design, where each participant was tested twice in a counter-balanced order (ie, once sober and once intoxicated at 1.1‰). On each appointment, the participants performed the S-R paradigm, which assesses automatic stimulus-response (S-R) binding within the framework of the theory of event coding (TEC). In short, the TEC states that stimulus features and responses become encoded in an event file when they occur simultaneously. These event files will be reactivated by any matching stimulus feature, thus facilitating the encoded response (and hampering different responses). Alcohol led to a general decrease in behavioral performance, as demonstrated by significant main effects of intoxication status on accuracy and response times (all P ≤.009). We also reproduced typical task effects, but did not find any significant interactions with the intoxication factor (all P ≥.099). The latter was further substantiated by Bayesian analyses providing positive to strong evidence for the null hypothesis. Taken together, our results demonstrate that even high-dose alcohol intoxication does not impair automatic response selection/S-R associations.
UR - http://www.scopus.com/inward/record.url?scp=85076345790&partnerID=8YFLogxK
U2 - 10.1111/adb.12852
DO - 10.1111/adb.12852
M3 - Journal articles
C2 - 31821661
AN - SCOPUS:85076345790
SN - 1355-6215
JO - Addiction Biology
JF - Addiction Biology
M1 - e12852
ER -