Auditory Deficits in Audiovisual Speech Perception in Adult Asperger’s Syndrome: fMRI Study

Fabian Alexander Tietze; Laura Hundertmark; Mandy Roy; Michael Zerr; Christopher Sinke; Daniel Wiswede; Martin Walter; Thomas F. Münte; Gregor R. Szycik

doi:10.3389/fpsyg.2019.02286

Auditory Deficits in Audiovisual Speech Perception in Adult Asperger’s Syndrome: fMRI Study

Fabian Alexander Tietze, Laura Hundertmark, Mandy Roy, Michael Zerr, Christopher Sinke, Daniel Wiswede, Martin Walter, Thomas F. Münte, Gregor R. Szycik^*

^*Corresponding author for this work

Department of Neurology

15 Citations (Scopus)

Abstract

Audiovisual (AV) integration deficits have been proposed to underlie difficulties in speech perception in Asperger’s syndrome (AS). It is not known, if the AV deficits are related to alterations in sensory processing at the level of unisensory processing or at levels of conjoint multisensory processing. Functional Magnetic-resonance images (MRI) was performed in 16 adult subjects with AS and 16 healthy controls (HC) matched for age, gender, and verbal IQ as they were exposed to disyllabic AV congruent and AV incongruent nouns. A simple semantic categorization task was used to ensure subjects’ attention to the stimuli. The left auditory cortex (BA41) showed stronger activation in HC than in subjects with AS with no interaction regarding AV congruency. This suggests that alterations in auditory processing in unimodal low-level areas underlie AV speech perception deficits in AS. Whether this is signaling a difficulty in the deployment of attention remains to be demonstrated.

Original language	English
Article number	2286
Journal	Frontiers in Psychology
Volume	10
ISSN	1664-1078
DOIs	https://doi.org/10.3389/fpsyg.2019.02286
Publication status	Published - 10.10.2019

Funding

Funding. We acknowledge support by the German Research Foundation (DFG) and the Open Access Publication Fund of Hannover Medical School (MHH).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 10 Reduced Inequalities

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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10.3389/fpsyg.2019.02286

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title = "Auditory Deficits in Audiovisual Speech Perception in Adult Asperger{\textquoteright}s Syndrome: fMRI Study",

abstract = "Audiovisual (AV) integration deficits have been proposed to underlie difficulties in speech perception in Asperger{\textquoteright}s syndrome (AS). It is not known, if the AV deficits are related to alterations in sensory processing at the level of unisensory processing or at levels of conjoint multisensory processing. Functional Magnetic-resonance images (MRI) was performed in 16 adult subjects with AS and 16 healthy controls (HC) matched for age, gender, and verbal IQ as they were exposed to disyllabic AV congruent and AV incongruent nouns. A simple semantic categorization task was used to ensure subjects{\textquoteright} attention to the stimuli. The left auditory cortex (BA41) showed stronger activation in HC than in subjects with AS with no interaction regarding AV congruency. This suggests that alterations in auditory processing in unimodal low-level areas underlie AV speech perception deficits in AS. Whether this is signaling a difficulty in the deployment of attention remains to be demonstrated.",

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AU - Sinke, Christopher

AU - Wiswede, Daniel

AU - Walter, Martin

AU - Münte, Thomas F.

AU - Szycik, Gregor R.

N1 - Funding Information: Funding. We acknowledge support by the German Research Foundation (DFG) and the Open Access Publication Fund of Hannover Medical School (MHH). Publisher Copyright: © Copyright © 2019 Tietze, Hundertmark, Roy, Zerr, Sinke, Wiswede, Walter, Münte and Szycik. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/10/10

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N2 - Audiovisual (AV) integration deficits have been proposed to underlie difficulties in speech perception in Asperger’s syndrome (AS). It is not known, if the AV deficits are related to alterations in sensory processing at the level of unisensory processing or at levels of conjoint multisensory processing. Functional Magnetic-resonance images (MRI) was performed in 16 adult subjects with AS and 16 healthy controls (HC) matched for age, gender, and verbal IQ as they were exposed to disyllabic AV congruent and AV incongruent nouns. A simple semantic categorization task was used to ensure subjects’ attention to the stimuli. The left auditory cortex (BA41) showed stronger activation in HC than in subjects with AS with no interaction regarding AV congruency. This suggests that alterations in auditory processing in unimodal low-level areas underlie AV speech perception deficits in AS. Whether this is signaling a difficulty in the deployment of attention remains to be demonstrated.

AB - Audiovisual (AV) integration deficits have been proposed to underlie difficulties in speech perception in Asperger’s syndrome (AS). It is not known, if the AV deficits are related to alterations in sensory processing at the level of unisensory processing or at levels of conjoint multisensory processing. Functional Magnetic-resonance images (MRI) was performed in 16 adult subjects with AS and 16 healthy controls (HC) matched for age, gender, and verbal IQ as they were exposed to disyllabic AV congruent and AV incongruent nouns. A simple semantic categorization task was used to ensure subjects’ attention to the stimuli. The left auditory cortex (BA41) showed stronger activation in HC than in subjects with AS with no interaction regarding AV congruency. This suggests that alterations in auditory processing in unimodal low-level areas underlie AV speech perception deficits in AS. Whether this is signaling a difficulty in the deployment of attention remains to be demonstrated.

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Auditory Deficits in Audiovisual Speech Perception in Adult Asperger’s Syndrome: fMRI Study

Abstract

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