Application of 3D-TOCSY-trNOESY for the assignment of bioactive ligands from mixtures

Lars Herfurth, Thomas Weimar, Thomas Peters*

*Corresponding author for this work
13 Citations (Scopus)

Abstract

With no prior knowledge of the identity of single components, a complete assignment of a bioactive ligand from a mixture of 15 carbohydrate ligands can be accomplished by utilizing NMR spectroscopy. A 3D-TOCSY-(transfer)NOESY experiment delivered essential information for the critical assignment of the glycosidic linkage type of the bioactive disaccharide (see scheme).

Original languageEnglish
JournalAngewandte Chemie - International Edition
Volume39
Issue number12
Pages (from-to)2097-2099
Number of pages3
ISSN1433-7851
DOIs
Publication statusPublished - 16.06.2000

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

Fingerprint

Dive into the research topics of 'Application of 3D-TOCSY-trNOESY for the assignment of bioactive ligands from mixtures'. Together they form a unique fingerprint.

Cite this