With no prior knowledge of the identity of single components, a complete assignment of a bioactive ligand from a mixture of 15 carbohydrate ligands can be accomplished by utilizing NMR spectroscopy. A 3D-TOCSY-(transfer)NOESY experiment delivered essential information for the critical assignment of the glycosidic linkage type of the bioactive disaccharide (see scheme).
|Angewandte Chemie - International Edition
|Number of pages
|Published - 16.06.2000
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)