Abstract
Abstract Introduction The geometry of the aortic annulus and implanted transcatheter aortic valve prosthesis might influence valve function. We investigated the influence of valve type and aortic valve calcification on post-implant geometry of catheter-based aortic valve prostheses. Methods Eighty consecutive patients with severe aortic valve stenosis (mean age 82 ± 6 years) underwent computed tomography before and after TAVI. Aortic annulus diameters were determined. Influence of prosthesis type and degree of aortic valve calcification on post-implant eccentricity were analysed. Results Aortic annulus eccentricity was reduced in patients after TAVI (0.21 ± 0.06 vs. 0.08 ± 0.06, p < 0.0001). Post-TAVI eccentricity was significantly lower in 65 patients following implantation of a balloon-expandable prosthesis as compared to 15 patients who received a self-expanding prosthesis (0.06 ± 0.05 vs. 0.15 ± 0.07, p < 0.0001), even though the extent of aortic valve calcification was not different. After TAVI, patients with a higher calcium amount retained a significantly higher eccentricity compared to patients with lower amounts of calcium. Conclusions Patients undergoing TAVI with a balloon-expandable prosthesis show a more circular shape of the implanted prosthesis as compared to patients with a self-expanding prosthesis. Eccentricity of the deployed prosthesis is affected by the extent of aortic valve calcification.
| Original language | English |
|---|---|
| Article number | 7090 |
| Journal | European Journal of Radiology |
| Volume | 84 |
| Issue number | 7 |
| Pages (from-to) | 1242-1248 |
| Number of pages | 7 |
| ISSN | 0720-048X |
| DOIs | |
| Publication status | Published - 01.07.2015 |
Funding
Dr. Nef received speaker honoraria from Edwards Life Science and Medtronic. Dr. Ensminger is both a proctor for Edwards Life Sciences receiving consulting fees and a proctor for Jenavalve Technology being in the Scientific Advisory Board. Dr. Feyrer is a proctor for Jenavalve Technology. Dr. Achenbach received speaker honoraria from Edwards Life Sciences and research grants from Siemens Healthcare and Abbott Vascular. Dr. Marwan received speaker honoraria from Siemens Healthcare and Edwards Lifesciences. This study was supported by the German Government, Bundesministerium für Bildung und Forschung ( 01EX1012B , “Spitzencluster Medical Valley“).