In order to determine the sensitivity of anticytoplasmic antibodies (ACPA-ANCA) in limited forms of Wegener's granulomatosis we have investigated 807 serum samples out of 222 patients with Wegener's granulomatosis. ACPA-ANCA has been detected in 64% of cases with active limited disease and in 94% of patients with active generalized disease. In contrast ACPA-ANCA has been observed in sera of patients in complete remission only in 43% (limited disease) and in 53% (generalized disease). So ACPA-ANCA appears to be of high diagnostic value even in the limited forms of Wegener's granulomatosis.
|Translated title of the contribution||Anticytoplasmatic Antibodies in Early Forms of Wegener's Disease|
|Number of pages||2|
|Publication status||Published - 07.1989|
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)