Antisense Arzneimittel gegen das humane interzelluläre Adhäsionsmolekül (ICAM-1)

Georg Sczakiel; Rosel Kretschmer-Kazemi Far

Antisense Arzneimittel gegen das humane interzelluläre Adhäsionsmolekül (ICAM-1)

Georg Sczakiel (Inventor), Rosel Kretschmer-Kazemi Far (Inventor)

Institute of Molecular Medicine

Abstract

The present invention relates to a specific antisense oligonucleotide which inhibits the expression of the adhesion molecule ICAM-1 in human cells. The present invention further relates to a vector containing said oligonucleotide and a host cell containing said vector or oligonucleotide and a pharmaceutical composition containing said oligonucleotide as well as uses thereof, in particular in the treatment of an inflammatory disease or condition in humans.

Original language	German
Patent number	EP3914710A1
Country/Territory	Germany
Priority date	25.01.19
Priority number	EP19153666.3
Publication status	Published - 25.01.2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

https://worldwide.espacenet.com/patent/search/family/065234475/publication/EP3914710A1?q=pn%3DEP3914710

Cite this

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title = "Antisense Arzneimittel gegen das humane interzellul{\"a}re Adh{\"a}sionsmolek{\"u}l (ICAM-1)",

abstract = "The present invention relates to a specific antisense oligonucleotide which inhibits the expression of the adhesion molecule ICAM-1 in human cells. The present invention further relates to a vector containing said oligonucleotide and a host cell containing said vector or oligonucleotide and a pharmaceutical composition containing said oligonucleotide as well as uses thereof, in particular in the treatment of an inflammatory disease or condition in humans.",

author = "Georg Sczakiel and \{Kretschmer-Kazemi Far\}, Rosel",

note = "Antisense Arzneimittel gegen das humane interzellul{\"a}re Adh{\"a}sionsmolek{\"u}l (ICAM-1) PVA 18069 Prio EP-Anmeldung PCT - Nachanmeldung validiert in EP 19 818 121.6, CN 201980089644.3, JP 2021-542136, KR 10-2021-7026805 , US 17/425,081 ; EP3914710A1",

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T1 - Antisense Arzneimittel gegen das humane interzelluläre Adhäsionsmolekül (ICAM-1)

AU - Sczakiel, Georg

AU - Kretschmer-Kazemi Far, Rosel

N1 - Antisense Arzneimittel gegen das humane interzelluläre Adhäsionsmolekül (ICAM-1) PVA 18069 Prio EP-Anmeldung PCT - Nachanmeldung validiert in EP 19 818 121.6, CN 201980089644.3, JP 2021-542136, KR 10-2021-7026805 , US 17/425,081

PY - 2019/1/25

Y1 - 2019/1/25

N2 - The present invention relates to a specific antisense oligonucleotide which inhibits the expression of the adhesion molecule ICAM-1 in human cells. The present invention further relates to a vector containing said oligonucleotide and a host cell containing said vector or oligonucleotide and a pharmaceutical composition containing said oligonucleotide as well as uses thereof, in particular in the treatment of an inflammatory disease or condition in humans.

AB - The present invention relates to a specific antisense oligonucleotide which inhibits the expression of the adhesion molecule ICAM-1 in human cells. The present invention further relates to a vector containing said oligonucleotide and a host cell containing said vector or oligonucleotide and a pharmaceutical composition containing said oligonucleotide as well as uses thereof, in particular in the treatment of an inflammatory disease or condition in humans.

M3 - Patente, Schutzrechte

M1 - EP3914710A1

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