Antibiotic resistance: Blocking tetracycline destruction

Sonja Petkovic, Winfried Hinrichs

Abstract

Enzymology and structural and functional characterization of some FAD-dependent monooxygenases provide insights into degradation of tetracycline antibiotics, but also show unexpected features of substrate recognition, reaction mechanism, and competitive inhibition.
Original languageEnglish
JournalNature Chemical Biology
Volume13
Issue number7
Pages (from-to)694-695
Number of pages2
ISSN1552-4450
DOIs
Publication statusPublished - 01.07.2017

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