Skip to main navigation Skip to search Skip to main content

[Anti-p200/anti-laminin gamma1 pemphigoid and BP180 NC16A/4575- positive mucous membrane pemphigoid : late diagnosis in a patient with disease-related loss of vision and multiple previous surgical interventions].

K M Kaune, M Kasperkiewicz, D Tams, M Bergmann, M Zutt

Abstract

A 87-year-old woman presented with a three-year history of partially erosive, partially bullous skin and mucosal lesions, symblepharon of both eyelids as well as dysphagia. To date, multiple excisions of the skin lesions, which had been described as "skin tumors" by surgeons, had been performed. The synopsis of histology, direct and indirect immunofluorescence established the diagnosis of anti-p200/anti-laminin gamma1 pemphigoid and BP180 NC16A/4575- positive mucous membrane pemphigoid with an unusual "epitope-spreading" phenomenon. Due to the late initiation of therapy, the disease-related loss of vision unfortunately was irreversible.
Original languageGerman
Title of host publicationDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
Number of pages5
Publication date2015
Pages60-64
ISBN (Print)1432-1173 (Electronic)\r0017-8470 (Linking)
DOIs
Publication statusPublished - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Cite this