Abstract
The sex chromosomes of the Megaselia scalaris wild-type strain Wien are homomorphic. We studied a roughly 1.8 kb X/Y DNA segment of this strain. It includes, at one end, the first part of a coding sequence for a protein of the vespid antigen 5 family. Molecular differentiation between the X and Y chromosomes has commenced, but homology, even of short DNA stretches, is still assessable beyond doubt. The most conspicuous differences between the X and the homologous Y segment were insertions/deletions in the noncoding region: among them, deletions, a duplication, and an insertion of a mobile element. These structural changes grossly disrupted homology. In comparison, base substitutions, though more numerous, contributed little to the differentiation of the X/Y DNA segment.
| Original language | English |
|---|---|
| Journal | Genome |
| Volume | 41 |
| Issue number | 2 |
| Pages (from-to) | 289-294 |
| Number of pages | 6 |
| ISSN | 0831-2796 |
| DOIs | |
| Publication status | Published - 1998 |
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)
