Alteration of early components of the visual evoked potential in amyotrophic lateral sclerosis

Thomas F. Münte; Mathias C. Tröger; Isabel Nusser; Bernardina M. Wieringa; Sönke Johannes; Mike Matzke; Reinhard Dengler

doi:10.1007/s004150050206

Alteration of early components of the visual evoked potential in amyotrophic lateral sclerosis

Thomas F. Münte^*, Mathias C. Tröger, Isabel Nusser, Bernardina M. Wieringa, Sönke Johannes, Mike Matzke, Reinhard Dengler

^*Corresponding author for this work

Clinic of Neurology

39 Citations (Scopus)

Abstract

Evoked potentials were recorded in three different visual experiments in 14 patients with amyotrophic lateral sclerosis (ALS) and 14 matched control subjects. Control subjects' evoked potentials (EPs) were characterized by an initial positivity in the 90-140 ms range (P1) at the temporo-occipital site. This component was absent from the group average of the ALS patients as well as the individual patients' EPs. As the P1 is known to emanate from inferior occipito-temporal areas, this finding provides electrophysiological evidence for a cortical involvement in ALS including visual areas.

Original language	English
Journal	Journal of Neurology
Volume	245
Issue number	4
Pages (from-to)	206-210
Number of pages	5
ISSN	0340-5354
DOIs	https://doi.org/10.1007/s004150050206
Publication status	Published - 11.05.1998

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Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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10.1007/s004150050206

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title = "Alteration of early components of the visual evoked potential in amyotrophic lateral sclerosis",

abstract = "Evoked potentials were recorded in three different visual experiments in 14 patients with amyotrophic lateral sclerosis (ALS) and 14 matched control subjects. Control subjects' evoked potentials (EPs) were characterized by an initial positivity in the 90-140 ms range (P1) at the temporo-occipital site. This component was absent from the group average of the ALS patients as well as the individual patients' EPs. As the P1 is known to emanate from inferior occipito-temporal areas, this finding provides electrophysiological evidence for a cortical involvement in ALS including visual areas.",

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AU - Münte, Thomas F.

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AU - Nusser, Isabel

AU - Wieringa, Bernardina M.

AU - Johannes, Sönke

AU - Matzke, Mike

AU - Dengler, Reinhard

PY - 1998/5/11

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N2 - Evoked potentials were recorded in three different visual experiments in 14 patients with amyotrophic lateral sclerosis (ALS) and 14 matched control subjects. Control subjects' evoked potentials (EPs) were characterized by an initial positivity in the 90-140 ms range (P1) at the temporo-occipital site. This component was absent from the group average of the ALS patients as well as the individual patients' EPs. As the P1 is known to emanate from inferior occipito-temporal areas, this finding provides electrophysiological evidence for a cortical involvement in ALS including visual areas.

AB - Evoked potentials were recorded in three different visual experiments in 14 patients with amyotrophic lateral sclerosis (ALS) and 14 matched control subjects. Control subjects' evoked potentials (EPs) were characterized by an initial positivity in the 90-140 ms range (P1) at the temporo-occipital site. This component was absent from the group average of the ALS patients as well as the individual patients' EPs. As the P1 is known to emanate from inferior occipito-temporal areas, this finding provides electrophysiological evidence for a cortical involvement in ALS including visual areas.

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ER -

Alteration of early components of the visual evoked potential in amyotrophic lateral sclerosis

Abstract

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