Abstract
Many plant allergens are glykoproteins. IgE-reactivity to the respective glykan moiety seldom seems to be of clinical significance. This appears to be different for a carbohydrate expressed on cells of non-primate mammals, prosimians and New World monkeys, the galactose-α-1,3-galactose (α-Gal). IgE-antibodies specific for α-Gal (anti-α-Gal-IgE) are associated with severe allergic symptoms and with a delayed-type anaphylaxis. The allergologically relevant carbohydrate determinants, therefore, differ considerably with regard to structure, occurrence, their association with clinical symptoms and the degree of severity.
| Translated title of the contribution | Immediate-type reactions and cross-reactive carbohydrate determinants (CCD) |
|---|---|
| Original language | German |
| Journal | Allergo Journal |
| Volume | 22 |
| Issue number | 1 |
| Pages (from-to) | 25-32 |
| Number of pages | 8 |
| ISSN | 0941-8849 |
| DOIs | |
| Publication status | Published - 01.01.2013 |
| Externally published | Yes |