Allergische Soforttypreaktionen und kreuzreaktive Kohlenhydratepitope (CCD)

Translated title of the contribution: Immediate-type reactions and cross-reactive carbohydrate determinants (CCD)

Uta Jappe*, Arnd Petersen, Monika Raulf-Heimsoth

*Corresponding author for this work
16 Citations (Scopus)


Many plant allergens are glykoproteins. IgE-reactivity to the respective glykan moiety seldom seems to be of clinical significance. This appears to be different for a carbohydrate expressed on cells of non-primate mammals, prosimians and New World monkeys, the galactose-α-1,3-galactose (α-Gal). IgE-antibodies specific for α-Gal (anti-α-Gal-IgE) are associated with severe allergic symptoms and with a delayed-type anaphylaxis. The allergologically relevant carbohydrate determinants, therefore, differ considerably with regard to structure, occurrence, their association with clinical symptoms and the degree of severity.

Translated title of the contributionImmediate-type reactions and cross-reactive carbohydrate determinants (CCD)
Original languageGerman
JournalAllergo Journal
Issue number1
Pages (from-to)25-32
Number of pages8
Publication statusPublished - 01.01.2013
Externally publishedYes


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