@article{dbd28e7bc1aa45e2b279064c8d1d3080,
title = "Aliphatic 1H, 13C and 15N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP+ and folate",
abstract = "Dihydrofolate reductase from the deep-sea bacterium Moritella profunda (MpDHFR) has been 13C/15N isotopically labelled and purified. Here, we report the aliphatic 1H, 13C and 15N resonance assignments of MpDHFR in complex with NADP+ and folate. The spectra of MpDHFR suggest considerably greater conformational heterogeneity than is seen in the closely related DHFR from Escherichia coli.",
author = "Loveridge, {E. Joel} and Matthews, {Stella M.} and Christopher Williams and Whittaker, {Sara B.M.} and G{\"u}nther, {Ulrich L.} and Evans, {Rhiannon M.} and Dawson, {William M.} and Crump, {Matthew P.} and Allemann, {Rudolf K.}",
note = "Funding Information: Acknowledgments This work was supported by the UK{\textquoteright}s Biotechnology and Biological Sciences Research Council (BBSRC) through grant BB/E008380/1 and Cardiff University. We thank the Wellcome Trust for open access to the Varian INOVA 900 MHz spectrometer at HWB-NMR, University of Birmingham, through Biomedical Resources grant 083796/Z/07/Z. We also thank the Wellcome Trust (WT082352MA) and the Engineering and Physical Sciences Research Council (EPSRC) (EP/F013515) for the Varian VNMRS 600 MHz cryo-probe at the University of Bristol. Copyright: Copyright 2013 Elsevier B.V., All rights reserved.",
year = "2013",
month = apr,
doi = "10.1007/s12104-012-9378-x",
language = "English",
volume = "7",
pages = "61--64",
journal = "Biomolecular NMR Assignments",
issn = "1874-2718",
number = "1",
}