AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2025

Marc Thill; Wolfgang Janni; Ute Susann Albert; Maggie Banys-Paluchowski; Rupert Bartsch; Ingo Bauerfeind; Vesna Bjelic-Radisic; Jens Blohmer; Wilfried Budach; Peter Dall; Nina Ditsch; Eva Maria Fallenberg; Peter A. Fasching; Tanja Fehm; Michael Friedrich; Bernd Gerber; Oleg Gluz; Nadia Harbeck; Andreas Hartkopf; Jörg Heil; Juliane Hörner-Rieber; Jens Huober; Hans Heinrich Kreipe; David Krug; Thorsten Kühn; Sherko Kümmel; Sibylle Loibl; Diana Lüftner; Michael Patrick Lux; Nicolai Maass; Christoph Mundhenke; Mattea Reinisch; Toralf Reimer; Kerstin Rhiem; Achim Rody; Marcus Schmidt; Andreas Schneeweiss; Florian Schütz; Hans Peter Sinn; Christine Solbach; Erich Franz Solomayer; Elmar Stickeler; Christoph Thomssen; Michael Untch; Marion van Mackelenbergh; Isabell Witzel; Achim Wöckel; Rachel Würstlein; Volkmar Müller; Tjoung Won Park-Simon

doi:10.1159/000545018

AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2025

Marc Thill^*, Wolfgang Janni, Ute Susann Albert, Maggie Banys-Paluchowski, Rupert Bartsch, Ingo Bauerfeind, Vesna Bjelic-Radisic, Jens Blohmer, Wilfried Budach, Peter Dall, Nina Ditsch, Eva Maria Fallenberg, Peter A. Fasching, Tanja Fehm, Michael Friedrich, Bernd Gerber, Oleg Gluz, Nadia Harbeck, Andreas Hartkopf, Jörg HeilJuliane Hörner-Rieber, Jens Huober, Hans Heinrich Kreipe, David Krug, Thorsten Kühn, Sherko Kümmel, Sibylle Loibl, Diana Lüftner, Michael Patrick Lux, Nicolai Maass, Christoph Mundhenke, Mattea Reinisch, Toralf Reimer, Kerstin Rhiem, Achim Rody, Marcus Schmidt, Andreas Schneeweiss, Florian Schütz, Hans Peter Sinn, Christine Solbach, Erich Franz Solomayer, Elmar Stickeler, Christoph Thomssen, Michael Untch, Marion van Mackelenbergh, Isabell Witzel, Achim Wöckel, Rachel Würstlein, Volkmar Müller, Tjoung Won Park-Simon

^*Corresponding author for this work

Department of Gynecology and Obstetrics

7 Citations (Scopus)

Abstract

The Breast Committee of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO; German Gynecological Oncology Group) presents the 2025 update of the evidence-based recommendations for the diagnosis and treatment of patients with locally advanced and metastatic breast cancer (mBC).

Original language	English
Journal	Breast Care
Volume	20
Issue number	3
Pages (from-to)	208-219
Number of pages	12
ISSN	1661-3791
DOIs	https://doi.org/10.1159/000545018
Publication status	Published - 01.06.2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Areas and Centers

Research Area: Luebeck Integrated Oncology Network (LION)
Centers: University Cancer Center Schleswig-Holstein (UCCSH)

DFG Research Classification Scheme

2.22-21 Gynaecology and Obstetrics

Access to Document

10.1159/000545018

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Thill, M., Janni, W., Albert, U. S., Banys-Paluchowski, M., Bartsch, R., Bauerfeind, I., Bjelic-Radisic, V., Blohmer, J., Budach, W., Dall, P., Ditsch, N., Fallenberg, E. M., Fasching, P. A., Fehm, T., Friedrich, M., Gerber, B., Gluz, O., Harbeck, N., Hartkopf, A., ... Park-Simon, T. W. (2025). AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2025. Breast Care, 20(3), 208-219. https://doi.org/10.1159/000545018

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title = "AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2025",

abstract = "The Breast Committee of the Arbeitsgemeinschaft Gyn{\"a}kologische Onkologie (AGO; German Gynecological Oncology Group) presents the 2025 update of the evidence-based recommendations for the diagnosis and treatment of patients with locally advanced and metastatic breast cancer (mBC).",

author = "Marc Thill and Wolfgang Janni and Albert, \{Ute Susann\} and Maggie Banys-Paluchowski and Rupert Bartsch and Ingo Bauerfeind and Vesna Bjelic-Radisic and Jens Blohmer and Wilfried Budach and Peter Dall and Nina Ditsch and Fallenberg, \{Eva Maria\} and Fasching, \{Peter A.\} and Tanja Fehm and Michael Friedrich and Bernd Gerber and Oleg Gluz and Nadia Harbeck and Andreas Hartkopf and J{\"o}rg Heil and Juliane H{\"o}rner-Rieber and Jens Huober and Kreipe, \{Hans Heinrich\} and David Krug and Thorsten K{\"u}hn and Sherko K{\"u}mmel and Sibylle Loibl and Diana L{\"u}ftner and Lux, \{Michael Patrick\} and Nicolai Maass and Christoph Mundhenke and Mattea Reinisch and Toralf Reimer and Kerstin Rhiem and Achim Rody and Marcus Schmidt and Andreas Schneeweiss and Florian Sch{\"u}tz and Sinn, \{Hans Peter\} and Christine Solbach and Solomayer, \{Erich Franz\} and Elmar Stickeler and Christoph Thomssen and Michael Untch and \{van Mackelenbergh\}, Marion and Isabell Witzel and Achim W{\"o}ckel and Rachel W{\"u}rstlein and Volkmar M{\"u}ller and Park-Simon, \{Tjoung Won\}",

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year = "2025",

month = jun,

day = "1",

doi = "10.1159/000545018",

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Thill, M, Janni, W, Albert, US, Banys-Paluchowski, M, Bartsch, R, Bauerfeind, I, Bjelic-Radisic, V, Blohmer, J, Budach, W, Dall, P, Ditsch, N, Fallenberg, EM, Fasching, PA, Fehm, T, Friedrich, M, Gerber, B, Gluz, O, Harbeck, N, Hartkopf, A, Heil, J, Hörner-Rieber, J, Huober, J, Kreipe, HH, Krug, D, Kühn, T, Kümmel, S, Loibl, S, Lüftner, D, Lux, MP, Maass, N, Mundhenke, C, Reinisch, M, Reimer, T, Rhiem, K, Rody, A, Schmidt, M, Schneeweiss, A, Schütz, F, Sinn, HP, Solbach, C, Solomayer, EF, Stickeler, E, Thomssen, C, Untch, M, van Mackelenbergh, M, Witzel, I, Wöckel, A, Würstlein, R, Müller, V & Park-Simon, TW 2025, 'AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2025', Breast Care, vol. 20, no. 3, pp. 208-219. https://doi.org/10.1159/000545018

TY - JOUR

T1 - AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer

T2 - Update 2025

AU - Thill, Marc

AU - Janni, Wolfgang

AU - Albert, Ute Susann

AU - Banys-Paluchowski, Maggie

AU - Bartsch, Rupert

AU - Bauerfeind, Ingo

AU - Bjelic-Radisic, Vesna

AU - Blohmer, Jens

AU - Budach, Wilfried

AU - Dall, Peter

AU - Ditsch, Nina

AU - Fallenberg, Eva Maria

AU - Fasching, Peter A.

AU - Fehm, Tanja

AU - Friedrich, Michael

AU - Gerber, Bernd

AU - Gluz, Oleg

AU - Harbeck, Nadia

AU - Hartkopf, Andreas

AU - Heil, Jörg

AU - Hörner-Rieber, Juliane

AU - Huober, Jens

AU - Kreipe, Hans Heinrich

AU - Krug, David

AU - Kühn, Thorsten

AU - Kümmel, Sherko

AU - Loibl, Sibylle

AU - Lüftner, Diana

AU - Lux, Michael Patrick

AU - Maass, Nicolai

AU - Mundhenke, Christoph

AU - Reinisch, Mattea

AU - Reimer, Toralf

AU - Rhiem, Kerstin

AU - Rody, Achim

AU - Schmidt, Marcus

AU - Schneeweiss, Andreas

AU - Schütz, Florian

AU - Sinn, Hans Peter

AU - Solbach, Christine

AU - Solomayer, Erich Franz

AU - Stickeler, Elmar

AU - Thomssen, Christoph

AU - Untch, Michael

AU - van Mackelenbergh, Marion

AU - Witzel, Isabell

AU - Wöckel, Achim

AU - Würstlein, Rachel

AU - Müller, Volkmar

AU - Park-Simon, Tjoung Won

PY - 2025/6/1

Y1 - 2025/6/1

N2 - The Breast Committee of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO; German Gynecological Oncology Group) presents the 2025 update of the evidence-based recommendations for the diagnosis and treatment of patients with locally advanced and metastatic breast cancer (mBC).

AB - The Breast Committee of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO; German Gynecological Oncology Group) presents the 2025 update of the evidence-based recommendations for the diagnosis and treatment of patients with locally advanced and metastatic breast cancer (mBC).

UR - https://www.scopus.com/pages/publications/105004384407

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U2 - 10.1159/000545018

DO - 10.1159/000545018

M3 - Scientific review articles

AN - SCOPUS:105004384407

SN - 1661-3791

VL - 20

SP - 208

EP - 219

JO - Breast Care

JF - Breast Care

IS - 3

ER -

AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2025

Abstract

UN SDGs

Research Areas and Centers

DFG Research Classification Scheme

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