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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
Brinda Ravikumar,
Rainer Duden
, David C. Rubinsztein
*
*
Corresponding author for this work
Institute of Biology
Addenbrooke's Hospital
849
Citations (Scopus)
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Neuroscience
Polyglutamine
100%
Autophagy
100%
Huntington's Disease
75%
Epoxomicin
75%
Sirolimus
75%
Alzheimer's Disease
25%
Parkinson's Disease
25%
Lysosome
25%
Muscular Dystrophy
25%
Exon
25%
Cell Line
25%
Cell Death
25%
Pharmacology, Toxicology and Pharmaceutical Science
Lactacystin
100%
Polyglutamine
100%
Huntington Chorea
75%
Rapamycin
75%
Epoxomicin
75%
Protein
25%
Enhanced Green Fluorescent Protein
25%
Oculopharyngeal Muscular Dystrophy
25%
Parkinson's Disease
25%
Alzheimer's Disease
25%
Alanine
25%
Biochemistry, Genetics and Molecular Biology
Autophagy
100%
Proteasome
50%
Cell Death
25%
Alanine
25%
Lysosome
25%
Soluble Protein
25%
Exon
25%