TY - JOUR
T1 - Age, metabolic control and type of insulin regime influences health-related quality of life in children and adolescents with type 1 diabetes mellitus
AU - Wagner, Verena M.
AU - Müller–Godeffroy, Esther
AU - Von Sengbusch, Simone
AU - Häger, Stefan
AU - Thyen, Ute
N1 - Funding Information:
Acknowledgements This study was supported by grants from the Association for Support of Rehabilitation Research LVA Schle-swig-Holstein-vffr, Germany (Verein zur Förderung der Rehabili-tationsforschung). We would like to thank the participating children, adolescents and their parents as well as staff members from the outpatient department of our hospital.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2005/7
Y1 - 2005/7
N2 - The effects of illness and treatment of diabetes mellitus extend beyond medical outcomes. We therefore evaluated health-related quality of life (HRQOL) in children (aged 8-12 years) and adolescents (aged 13-16 years) with type 1 diabetes to compare their results with healthy peers and to identify HRQOL determinants. A total of 68 children and adolescents from a tertiary care clinic which specialises in the management of diabetes, completed the generic KINDL-R questionnaire. This instrument for children and adolescents has six dimensions and an additional module assessing condition-related HRQOL. Overall, the HRQOL was not different between patients with type 1 diabetes and healthy controls. In some areas, children and adolescents with diabetes reported a better HRQOL compared to healthy peers: adolescents reported better psychological well-being ( P <0.05) and children higher levels of well-being in the school domain ( P <0.05). In general, children reported a better HRQOL ( P <0.05) than adolescents with type 1 diabetes confirming age-related differences in HRQOL in the general population. Lower HbA1c (<8%) and intensified insulin therapy (>3 injections/day) were associated with a better HRQOL in different domains ( P <0.05). The subscale "chronic illness" showed a better HRQOL ( P <0.001) in children and adolescents with diabetes compared to age-matched controls with other chronic conditions. Conclusion:Children and adolescents from a paediatric department specialising in diabetes management report good health-related quality of life. Younger age, good metabolic control and intensified insulin therapy are associated with a better health-related quality of life. Dimensions of health-related quality of life appear to play different roles at different ages, emphasising the importance of the multidimensional health-related quality of life concept and the value of age-appropriate self-reports.
AB - The effects of illness and treatment of diabetes mellitus extend beyond medical outcomes. We therefore evaluated health-related quality of life (HRQOL) in children (aged 8-12 years) and adolescents (aged 13-16 years) with type 1 diabetes to compare their results with healthy peers and to identify HRQOL determinants. A total of 68 children and adolescents from a tertiary care clinic which specialises in the management of diabetes, completed the generic KINDL-R questionnaire. This instrument for children and adolescents has six dimensions and an additional module assessing condition-related HRQOL. Overall, the HRQOL was not different between patients with type 1 diabetes and healthy controls. In some areas, children and adolescents with diabetes reported a better HRQOL compared to healthy peers: adolescents reported better psychological well-being ( P <0.05) and children higher levels of well-being in the school domain ( P <0.05). In general, children reported a better HRQOL ( P <0.05) than adolescents with type 1 diabetes confirming age-related differences in HRQOL in the general population. Lower HbA1c (<8%) and intensified insulin therapy (>3 injections/day) were associated with a better HRQOL in different domains ( P <0.05). The subscale "chronic illness" showed a better HRQOL ( P <0.001) in children and adolescents with diabetes compared to age-matched controls with other chronic conditions. Conclusion:Children and adolescents from a paediatric department specialising in diabetes management report good health-related quality of life. Younger age, good metabolic control and intensified insulin therapy are associated with a better health-related quality of life. Dimensions of health-related quality of life appear to play different roles at different ages, emphasising the importance of the multidimensional health-related quality of life concept and the value of age-appropriate self-reports.
UR - http://www.scopus.com/inward/record.url?scp=23044442683&partnerID=8YFLogxK
U2 - 10.1007/s00431-005-1681-4
DO - 10.1007/s00431-005-1681-4
M3 - Journal articles
C2 - 15875213
AN - SCOPUS:23044442683
SN - 0340-6199
VL - 164
SP - 491
EP - 496
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
IS - 8
ER -
