Advances in large area robotically assisted OCT (LARA-OCT): towards drive-by continuous motion imaging

Madita Göb; Simon Lotz; Linh Ha-Wissel; Sazgar Burhan; Sven Böttger; Floris Ernst; Jennifer Hundt; Robert Huber

doi:10.1117/12.2670950

Advances in large area robotically assisted OCT (LARA-OCT): towards drive-by continuous motion imaging

Madita Göb, Simon Lotz, Linh Ha-Wissel, Sazgar Burhan, Sven Böttger, Floris Ernst, Jennifer Hundt, Robert Huber

Abstract

Optical coherence tomography is a powerful imaging technique to visualize and localize depth-dependent tissue structure to differentiate between healthy and pathological conditions. However, conventional OCT systems are only capable of detecting small areas. To overcome this limitation, we have developed a large area robotically assisted OCT (LARA-OCT) system for automatic acquisition of large OCT images. Using mosaic pattern acquisition and subsequent stitching, we previously demonstrated initial in vivo OCT skin images beyond 10 cm². To improve acquisition speed and reduce dead times, we here demonstrate and analyze LARA-OCT with a new drive-by continuous motion imaging protocol.

Original language	English
Title of host publication	Optical Coherence Imaging Techniques and Imaging in Scattering Media V
Editors	Benjamin J. Vakoc, Maciej Wojtkowski, Yoshiaki Yasuno
Volume	12632
Publisher	SPIE
Publication date	11.08.2023
Pages	126321N
DOIs	https://doi.org/10.1117/12.2670950
Publication status	Published - 11.08.2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 9 Industry, Innovation, and Infrastructure

Research Areas and Centers

Academic Focus: Biomedical Engineering

DFG Research Classification Scheme

2.22-32 Medical Physics, Biomedical Technology

Access to Document

10.1117/12.2670950

https://doi.org/10.1117/12.2670950

Cite this

Göb, M., Lotz, S., Ha-Wissel, L., Burhan, S., Böttger, S., Ernst, F., Hundt, J., & Huber, R. (2023). Advances in large area robotically assisted OCT (LARA-OCT): towards drive-by continuous motion imaging. In B. J. Vakoc, M. Wojtkowski, & Y. Yasuno (Eds.), Optical Coherence Imaging Techniques and Imaging in Scattering Media V (Vol. 12632, pp. 126321N). SPIE. https://doi.org/10.1117/12.2670950

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title = "Advances in large area robotically assisted OCT (LARA-OCT): towards drive-by continuous motion imaging",

abstract = "Optical coherence tomography is a powerful imaging technique to visualize and localize depth-dependent tissue structure to differentiate between healthy and pathological conditions. However, conventional OCT systems are only capable of detecting small areas. To overcome this limitation, we have developed a large area robotically assisted OCT (LARA-OCT) system for automatic acquisition of large OCT images. Using mosaic pattern acquisition and subsequent stitching, we previously demonstrated initial in vivo OCT skin images beyond 10 cm². To improve acquisition speed and reduce dead times, we here demonstrate and analyze LARA-OCT with a new drive-by continuous motion imaging protocol.",

author = "Madita G{\"o}b and Simon Lotz and Linh Ha-Wissel and Sazgar Burhan and Sven B{\"o}ttger and Floris Ernst and Jennifer Hundt and Robert Huber",

year = "2023",

month = aug,

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doi = "10.1117/12.2670950",

language = "English",

volume = "12632",

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Göb, M , Lotz, S, Ha-Wissel, L, Burhan, S, Böttger, S, Ernst, F , Hundt, J & Huber, R 2023, Advances in large area robotically assisted OCT (LARA-OCT): towards drive-by continuous motion imaging. in BJ Vakoc, M Wojtkowski & Y Yasuno (eds), Optical Coherence Imaging Techniques and Imaging in Scattering Media V. vol. 12632, SPIE, pp. 126321N. https://doi.org/10.1117/12.2670950

Advances in large area robotically assisted OCT (LARA-OCT): towards drive-by continuous motion imaging. / Göb, Madita ; Lotz, Simon; Ha-Wissel, Linh et al.
Optical Coherence Imaging Techniques and Imaging in Scattering Media V. ed. / Benjamin J. Vakoc; Maciej Wojtkowski; Yoshiaki Yasuno. Vol. 12632 SPIE, 2023. p. 126321N.

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

TY - GEN

T1 - Advances in large area robotically assisted OCT (LARA-OCT): towards drive-by continuous motion imaging

AU - Göb, Madita

AU - Lotz, Simon

AU - Ha-Wissel, Linh

AU - Burhan, Sazgar

AU - Böttger, Sven

AU - Ernst, Floris

AU - Hundt, Jennifer

AU - Huber, Robert

PY - 2023/8/11

Y1 - 2023/8/11

N2 - Optical coherence tomography is a powerful imaging technique to visualize and localize depth-dependent tissue structure to differentiate between healthy and pathological conditions. However, conventional OCT systems are only capable of detecting small areas. To overcome this limitation, we have developed a large area robotically assisted OCT (LARA-OCT) system for automatic acquisition of large OCT images. Using mosaic pattern acquisition and subsequent stitching, we previously demonstrated initial in vivo OCT skin images beyond 10 cm². To improve acquisition speed and reduce dead times, we here demonstrate and analyze LARA-OCT with a new drive-by continuous motion imaging protocol.

AB - Optical coherence tomography is a powerful imaging technique to visualize and localize depth-dependent tissue structure to differentiate between healthy and pathological conditions. However, conventional OCT systems are only capable of detecting small areas. To overcome this limitation, we have developed a large area robotically assisted OCT (LARA-OCT) system for automatic acquisition of large OCT images. Using mosaic pattern acquisition and subsequent stitching, we previously demonstrated initial in vivo OCT skin images beyond 10 cm². To improve acquisition speed and reduce dead times, we here demonstrate and analyze LARA-OCT with a new drive-by continuous motion imaging protocol.

U2 - 10.1117/12.2670950

DO - 10.1117/12.2670950

M3 - Conference contribution

VL - 12632

SP - 126321N

BT - Optical Coherence Imaging Techniques and Imaging in Scattering Media V

A2 - Vakoc, Benjamin J.

A2 - Wojtkowski, Maciej

A2 - Yasuno, Yoshiaki

PB - SPIE

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