Acute renal failure associated with bilateral enlargement of the kidneys: A rare manifestation of acute lymphoblastic leukemia (ALL)

H. Escobar; K. Häffner; Moritz Pohl; H. Hopfer; O. Determann; M. Lauten; U. Kontny

doi:10.1055/s-0029-1216365

Acute renal failure associated with bilateral enlargement of the kidneys: A rare manifestation of acute lymphoblastic leukemia (ALL)

H. Escobar, K. Häffner, Moritz Pohl, H. Hopfer, O. Determann, M. Lauten, U. Kontny^*

^*Corresponding author for this work

Clinic of Pediatric and Adolescent Medicine

2 Citations (Scopus)

Abstract

We report a 6-year-old patient who presented with acute renal failure resolving after vigorous intravenous hydration. Renal biopsy was taken because of unexplained enlargement of both kidneys. Histological workup showed infiltration by lymphoblasts while blood counts showed a normal differential. Subsequent bone marrow aspiration revealed 34% lymphoblasts of T-lineage origin, leading to the diagnosis of T-ALL. This case underlines that malignant hematologic infiltration should be considered in patients presenting with unexplained renal failure and enlarged kidneys.

Original language	English
Journal	Klinische Padiatrie
Volume	221
Issue number	3
Pages (from-to)	176-178
Number of pages	3
ISSN	0300-8630
DOIs	https://doi.org/10.1055/s-0029-1216365
Publication status	Published - 2009

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Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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abstract = "We report a 6-year-old patient who presented with acute renal failure resolving after vigorous intravenous hydration. Renal biopsy was taken because of unexplained enlargement of both kidneys. Histological workup showed infiltration by lymphoblasts while blood counts showed a normal differential. Subsequent bone marrow aspiration revealed 34% lymphoblasts of T-lineage origin, leading to the diagnosis of T-ALL. This case underlines that malignant hematologic infiltration should be considered in patients presenting with unexplained renal failure and enlarged kidneys.",

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AU - Escobar, H.

AU - Häffner, K.

AU - Pohl, Moritz

AU - Hopfer, H.

AU - Determann, O.

AU - Lauten, M.

AU - Kontny, U.

PY - 2009

Y1 - 2009

N2 - We report a 6-year-old patient who presented with acute renal failure resolving after vigorous intravenous hydration. Renal biopsy was taken because of unexplained enlargement of both kidneys. Histological workup showed infiltration by lymphoblasts while blood counts showed a normal differential. Subsequent bone marrow aspiration revealed 34% lymphoblasts of T-lineage origin, leading to the diagnosis of T-ALL. This case underlines that malignant hematologic infiltration should be considered in patients presenting with unexplained renal failure and enlarged kidneys.

AB - We report a 6-year-old patient who presented with acute renal failure resolving after vigorous intravenous hydration. Renal biopsy was taken because of unexplained enlargement of both kidneys. Histological workup showed infiltration by lymphoblasts while blood counts showed a normal differential. Subsequent bone marrow aspiration revealed 34% lymphoblasts of T-lineage origin, leading to the diagnosis of T-ALL. This case underlines that malignant hematologic infiltration should be considered in patients presenting with unexplained renal failure and enlarged kidneys.

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ER -

Acute renal failure associated with bilateral enlargement of the kidneys: A rare manifestation of acute lymphoblastic leukemia (ALL)

Abstract

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