Activation of a ductal-to-endocrine transdifferentiation transcriptional program in the pancreatic cancer cell line PANC-1 is controlled by Rac1 and RAC1b through antagonistic regulation of stemness factors

Paula Marie Schmidtlein, Clara Volz, Alexander Hackel, Isabel Thürling, Darko Castven, Rüdiger Braun, Ulrich Friedrich Wellner, Björn Konukiewitz, Gabriela Riemekasten, Hendrik Lehnert, Jens Uwe Marquardt, Hendrik Ungefroren*

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology