TY - JOUR
T1 - A survival score for patients receiving stereotactic radiosurgery alone for brain metastases from breast cancer
AU - Rades, Dirk
AU - Dziggel, Liesa
AU - Janssen, Stefan
AU - Blanck, Oliver
AU - Hornung, Dagmar
AU - Schild, Steven E.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/3
Y1 - 2016/3
N2 - Aim: To generate a survival score for patients with breast cancer treated with stereotactic radiosurgery (SRS) alone for brain metastases. Patients and Methods: Seven factors were evaluated in 34 patients, namely age, performance score, number of brain metastases, maximum diameter of all brain metastases, location of brain metastases, extracerebral metastases and time between breast cancer diagnosis and SRS. The score was created from factors having a significant impact on survival. Points of 0 (worse survival) or 1 (better survival) were assigned. Factor scores were added to total prognostic scores for each patient. Results: A significant impact on survival was found for performance score (p<0.001), maximum diameter of cerebral lesions (p=0.002), and extracerebral metastases (p=0.026). Three groups were designated by score: 0-1, 2 and 3 points. One-year survival rates were 48%, 71% and 100%, respectively (p<0.001). Conclusion: This score contributes to appropriate selection of personalized treatment in patients with breast cancer with few cerebral metastases.
AB - Aim: To generate a survival score for patients with breast cancer treated with stereotactic radiosurgery (SRS) alone for brain metastases. Patients and Methods: Seven factors were evaluated in 34 patients, namely age, performance score, number of brain metastases, maximum diameter of all brain metastases, location of brain metastases, extracerebral metastases and time between breast cancer diagnosis and SRS. The score was created from factors having a significant impact on survival. Points of 0 (worse survival) or 1 (better survival) were assigned. Factor scores were added to total prognostic scores for each patient. Results: A significant impact on survival was found for performance score (p<0.001), maximum diameter of cerebral lesions (p=0.002), and extracerebral metastases (p=0.026). Three groups were designated by score: 0-1, 2 and 3 points. One-year survival rates were 48%, 71% and 100%, respectively (p<0.001). Conclusion: This score contributes to appropriate selection of personalized treatment in patients with breast cancer with few cerebral metastases.
UR - http://www.scopus.com/inward/record.url?scp=84991717816&partnerID=8YFLogxK
M3 - Journal articles
C2 - 26977000
AN - SCOPUS:84991717816
SN - 0250-7005
VL - 36
SP - 1073
EP - 1076
JO - Anticancer Research
JF - Anticancer Research
IS - 3
ER -
