A rigid lanthanide binding tag for NMR structural analysis of carbohydrates

Alvaro Mallagaray; Angeles Canales; Gema Domínguez; Jesús Jiménez-Barbero; Javier Pérez-Castells

doi:10.1039/c1cc11860a

A rigid lanthanide binding tag for NMR structural analysis of carbohydrates

Alvaro Mallagaray, Angeles Canales, Gema Domínguez, Jesús Jiménez-Barbero^*, Javier Pérez-Castells

^*Corresponding author for this work

Institute of Chemistry and Metabolomics

30 Citations (Scopus)

Abstract

The first synthesis of a carbohydrate molecule covalently bound to a rigid lanthanide binding tag is reported. This derivative has been designed as a new tool to provide long-range restraints for structural elucidation and molecular recognition studies of carbohydrates, thus extending the methodology already developed for proteins.

Original language	English
Journal	Chemical Communications
Volume	47
Issue number	25
Pages (from-to)	7179-7181
Number of pages	3
ISSN	1359-7345
DOIs	https://doi.org/10.1039/c1cc11860a
Publication status	Published - 2011

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Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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abstract = "The first synthesis of a carbohydrate molecule covalently bound to a rigid lanthanide binding tag is reported. This derivative has been designed as a new tool to provide long-range restraints for structural elucidation and molecular recognition studies of carbohydrates, thus extending the methodology already developed for proteins.",

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AU - Domínguez, Gema

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AU - Pérez-Castells, Javier

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EP - 7181

JO - Chemical Communications

JF - Chemical Communications

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A rigid lanthanide binding tag for NMR structural analysis of carbohydrates

Abstract

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