A randomized trial (RAREST-01) comparing Mepitel® Film and standard care for prevention of radiation dermatitis in patients irradiated for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN)

Dirk Rades*, Carlos A. Narvaez, Laura Splettstößer, Claudia Dömer, Cornelia Setter, Christian Idel, Julika Ribbat-Idel, Sven Perner, Tobias Bartscht, Denise Olbrich, Steven E. Schild, Jesper Carl

*Corresponding author for this work
3 Citations (Scopus)

Abstract

Mepitel® Film (MEP) and standard care (STD) were compared for radiation dermatitis in SCCHN patients. This trial was stopped prematurely since13/28 patients did not tolerate MEP. Grade ≥2 dermatitis: 34.8% (MEP) vs. 35.7% (STD) at 50 Gy, 65.2% vs. 59.3% at 60 Gy. MEP was unsatisfactorily tolerated and appeared not superior (NCT03047174).

Original languageEnglish
JournalRadiotherapy and Oncology
Volume139
Pages (from-to)79-82
Number of pages4
ISSN0167-8140
DOIs
Publication statusPublished - 10.2019

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