A novel reverse genetics system for human norovirus

Stefan Taube; Christiane E. Wobus

doi:10.1016/j.tim.2014.10.001

A novel reverse genetics system for human norovirus

Stefan Taube, Christiane E. Wobus^*

^*Corresponding author for this work

Institute of Virology and Cell Biology

University of Michigan

5 Citations (Scopus)

Abstract

Human noroviruses cause significant morbidity, mortality, and economic losses worldwide. The inability to grow human noroviruses in cell culture has hampered our collective understanding of virus-host interactions and development of therapeutics. A newly described single-plasmid reverse genetics system for noroviruses has the potential to facilitate basic and applied research.

Original language	English
Journal	Trends in Microbiology
Volume	22
Issue number	11
Pages (from-to)	604-606
Number of pages	3
ISSN	0966-842X
DOIs	https://doi.org/10.1016/j.tim.2014.10.001
Publication status	Published - 01.01.2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Areas and Centers

Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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10.1016/j.tim.2014.10.001

Cite this

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title = "A novel reverse genetics system for human norovirus",

abstract = "Human noroviruses cause significant morbidity, mortality, and economic losses worldwide. The inability to grow human noroviruses in cell culture has hampered our collective understanding of virus-host interactions and development of therapeutics. A newly described single-plasmid reverse genetics system for noroviruses has the potential to facilitate basic and applied research.",

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AU - Taube, Stefan

AU - Wobus, Christiane E.

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AB - Human noroviruses cause significant morbidity, mortality, and economic losses worldwide. The inability to grow human noroviruses in cell culture has hampered our collective understanding of virus-host interactions and development of therapeutics. A newly described single-plasmid reverse genetics system for noroviruses has the potential to facilitate basic and applied research.

UR - https://www.scopus.com/pages/publications/84926672923

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DO - 10.1016/j.tim.2014.10.001

M3 - Short survey

C2 - 25438616

AN - SCOPUS:84926672923

SN - 0966-842X

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SP - 604

EP - 606

JO - Trends in Microbiology

JF - Trends in Microbiology

IS - 11

ER -

A novel reverse genetics system for human norovirus

Abstract

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