In this paper we describe a new algorithm for nonrigid registration of brain images based on an elastically deformable model. The use of registration methods has become an important tool for computer-assisted diagnosis and surgery. Our goal was to improve analysis in various applications of neurology and neurosurgery by improving nonrigid registration. A local gray level similarity measure is used to make an initial sparse displacement field estimate. The field is initially estimated at locations determined by local features, and then a linear elastic model is used to infer the volumetric deformation across the image. The associated partial differential equation is solved by a finite element approach. A model of empirically observed variability of the brain was created from a dataset of 154 young adults. Both homogeneous and inhomogeneous elasticity models were compared. The algorithm has been applied to medical applications including intraoperative images of neurosurgery showing brain shift and a study of gait and balance disorder.
|Title of host publication||MICCAI 2001: Medical Image Computing and Computer-Assisted Intervention – MICCAI 2001|
|Number of pages||9|
|Publication status||Published - 01.01.2001|
|Event||4th International Conference on Medical Image Computing and Computer-Assisted Intervention |
- Utrecht, Netherlands
Duration: 14.10.2001 → 17.10.2001
Conference number: 130079