TY - JOUR
T1 - A new survival score for patients scheduled for palliative irradiation of locally advanced carcinoma of the head-and-neck
AU - Rades, Dirk
AU - Staackmann, Christian
AU - Ribbat-Idel, Julika
AU - Perner, Sven
AU - Idel, Christian
AU - Bruchhage, Karl L.
AU - Hakim, Samer G.
AU - Schild, Steven E.
N1 - Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
PY - 2021/6
Y1 - 2021/6
N2 - Background/Aim: Patients with advanced squamous cell carcinoma of the head-and-neck (SCCHN) may be assigned to palliative irradiation. A survival score was developed for this group to support treatment personalization. Patients and Methods: Seventy-eight patients who received palliative irradiation for SCCHN and had complete data regarding performance score, pre-radiotherapy hemoglobin levels, and main tumor site were included in this retrospective study. Six-month survival rates of these factors were divided by 10 (factor scores) and added for each patient (total patient scores). Results: Total patient scores ranged between 8 and 15 points. Three groups were designed based on the 6-month survival rates, namely 8-9 (n=15), 11-13 (n=36), and 14-15 (n=27) points. Six-month survival rates were 13%, 28%, and 63%, and median survival times were 1, 2, and 11 months (p=0.001). Conclusion: A new survival score including three prognostic groups was developed. This new tool can help physicians when designing personalized treatments for patients with SCCHN scheduled for palliative irradiation.
AB - Background/Aim: Patients with advanced squamous cell carcinoma of the head-and-neck (SCCHN) may be assigned to palliative irradiation. A survival score was developed for this group to support treatment personalization. Patients and Methods: Seventy-eight patients who received palliative irradiation for SCCHN and had complete data regarding performance score, pre-radiotherapy hemoglobin levels, and main tumor site were included in this retrospective study. Six-month survival rates of these factors were divided by 10 (factor scores) and added for each patient (total patient scores). Results: Total patient scores ranged between 8 and 15 points. Three groups were designed based on the 6-month survival rates, namely 8-9 (n=15), 11-13 (n=36), and 14-15 (n=27) points. Six-month survival rates were 13%, 28%, and 63%, and median survival times were 1, 2, and 11 months (p=0.001). Conclusion: A new survival score including three prognostic groups was developed. This new tool can help physicians when designing personalized treatments for patients with SCCHN scheduled for palliative irradiation.
UR - http://www.scopus.com/inward/record.url?scp=85107655344&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/74f4f756-3ebd-30aa-a3db-9d629951916c/
U2 - 10.21873/anticanres.15088
DO - 10.21873/anticanres.15088
M3 - Journal articles
C2 - 34083297
AN - SCOPUS:85107655344
SN - 0250-7005
VL - 41
SP - 3055
EP - 3058
JO - Anticancer Research
JF - Anticancer Research
IS - 6
ER -