A mathematical model for the respiratory central pattern generator

Annika Multusch; Eike Petersen

A mathematical model for the respiratory central pattern generator

Annika Multusch, Eike Petersen

Institute of Electrical Engineering in Medicine

Abstract

The respiratory Central Pattern Generator (rCPG) is a neural circuit located in the brainstem, generating the physiological rhythmic breathing pattern of alternating inspiration and expiration. In this work, we propose a mathematical model of the rCPG which incorporates physiological feedback mechanisms. Numerical simulations of a closed-loop model of the rCPG with a lung and gas exchange model confirm the ability of the proposed model to reproduce the behavior of the rCPG in several important physiological regimes.

Original language	English
Number of pages	2
Publication status	Published - 03.2020
Event	AUTOMED - Automation in Medical Engineering 2020 - Lübeck, Germany Duration: 02.03.2020 → 03.03.2020

Conference

Conference	AUTOMED - Automation in Medical Engineering 2020
Country/Territory	Germany
City	Lübeck
Period	02.03.20 → 03.03.20

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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https://journals.infinite-science.de/index.php/automed/article/view/331

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title = "A mathematical model for the respiratory central pattern generator",

abstract = "The respiratory Central Pattern Generator (rCPG) is a neural circuit located in the brainstem, generating the physiological rhythmic breathing pattern of alternating inspiration and expiration. In this work, we propose a mathematical model of the rCPG which incorporates physiological feedback mechanisms. Numerical simulations of a closed-loop model of the rCPG with a lung and gas exchange model confirm the ability of the proposed model to reproduce the behavior of the rCPG in several important physiological regimes.",

author = "Annika Multusch and Eike Petersen",

year = "2020",

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language = "English",

note = "AUTOMED - Automation in Medical Engineering 2020 ; Conference date: 02-03-2020 Through 03-03-2020",

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TY - CONF

T1 - A mathematical model for the respiratory central pattern generator

AU - Multusch, Annika

AU - Petersen, Eike

PY - 2020/3

Y1 - 2020/3

N2 - The respiratory Central Pattern Generator (rCPG) is a neural circuit located in the brainstem, generating the physiological rhythmic breathing pattern of alternating inspiration and expiration. In this work, we propose a mathematical model of the rCPG which incorporates physiological feedback mechanisms. Numerical simulations of a closed-loop model of the rCPG with a lung and gas exchange model confirm the ability of the proposed model to reproduce the behavior of the rCPG in several important physiological regimes.

AB - The respiratory Central Pattern Generator (rCPG) is a neural circuit located in the brainstem, generating the physiological rhythmic breathing pattern of alternating inspiration and expiration. In this work, we propose a mathematical model of the rCPG which incorporates physiological feedback mechanisms. Numerical simulations of a closed-loop model of the rCPG with a lung and gas exchange model confirm the ability of the proposed model to reproduce the behavior of the rCPG in several important physiological regimes.

M3 - Conference Papers

T2 - AUTOMED - Automation in Medical Engineering 2020

Y2 - 2 March 2020 through 3 March 2020

ER -

A mathematical model for the respiratory central pattern generator

Abstract

Conference

UN SDGs

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