A mathematical description of nerve fiber bundle trajectories and their variability in the human retina

N. M. Jansonius*, J. Nevalainen, B. Selig, L. M. Zangwill, P. A. Sample, W. M. Budde, J. B. Jonas, W. A. Lagrèze, P. J. Airaksinen, R. Vonthein, L. A. Levin, J. Paetzold, U. Schiefer

*Corresponding author for this work
83 Citations (Scopus)

Abstract

We developed a mathematical model wherein retinal nerve fiber trajectories can be described and the corresponding inter-subject variability analyzed. The model was based on traced nerve fiber bundle trajectories extracted from 55 fundus photographs of 55 human subjects. The model resembled the typical retinal nerve fiber layer course within 20° eccentricity. Depending on the location of the visual field test point, the standard deviation of the calculated corresponding angular location at the optic nerve head circumference ranged from less than 1° to 18°, with an average of 8.8°.

Original languageEnglish
JournalVision Research
Volume49
Issue number17
Pages (from-to)2157-2163
Number of pages7
ISSN0042-6989
DOIs
Publication statusPublished - 28.08.2009

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