A long-range repeat cluster in chromosome 1 of the house mouse, Mus musculus, and its relation to a germline homogeneously staining region

L. Purmann*, C. Plass, M. Grüneberg, H. Winking, W. Traut

*Corresponding author for this work
19 Citations (Scopus)

Abstract

The laboratory mouse C57BL genome contains about 50 copies of a long-range repeat DNA family clustered in the C-D region of chromosome 1. The repeat length is more than 50 kb and includes sequences homologous to at least two mRNAs. There are small differences in the copies of this repeat family such as restriction site mutations and gross differences like rearrangements and insertions of LINE1 elements. A germline homogeneously staining region occurring as a chromosome 1 polymorphism in many feral populations of the house mouse is an amplified version of this long-range repeat cluster.

Original languageEnglish
JournalGenomics
Volume12
Issue number1
Pages (from-to)80-88
Number of pages9
ISSN0888-7543
DOIs
Publication statusPublished - 01.1992

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

Fingerprint

Dive into the research topics of 'A long-range repeat cluster in chromosome 1 of the house mouse, Mus musculus, and its relation to a germline homogeneously staining region'. Together they form a unique fingerprint.

Cite this