TY - JOUR
T1 - A concept for a magnetic particle imaging scanner with Halbach arrays
AU - Bakenecker, A. C.
AU - Schumacher, J.
AU - Blümler, P.
AU - Gräfe, K.
AU - Ahlborg, M.
AU - Buzug, T. M.
N1 - Funding Information:
The authors gratefully acknowledge the Federal Ministry of Education and Research, Germany (BMBF) for funding this project under Grant Nos. 13GW0230B (FMT), 13GW0071D (SKAMPI), 01DL17010A (IMAGINE).
Publisher Copyright:
© 2020 Institute of Physics and Engineering in Medicine
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/10/7
Y1 - 2020/10/7
N2 - Magnetic particle imaging (MPI) is a new medical imaging technique visualizing the concentration distribution of superparamagnetic nanoparticles used as tracer material. MPI is not yet in clinical routine, since one of the challenges is the upscaling of scanners. Typically, the magnetic fields of MPI scanners are generated electromagnetically, resulting in an immense power consumption but providing high flexibility in terms of adjusting the field strengths and very fast image acquisition rates. Permanent magnets provide high flux densities and do not need any power supply. However, the flux density is not adjustable, and a mechanical movement is slow compared to electromagnetically varying fields. The MPI scanner concept proposed here uses permanent magnets and provides high flexibility, with the possibility to choose between fast overview scanning and detailed image acquisition. By mechanical rotation of magnetic rings in Halbach array configuration, it is possible to adjust the field or gradient strengths. The latter allows for determining the spatial resolution and the size of the field of view. A continuous mechanical rotation defines the coarseness of the scanning trajectory and image acquisition rate. This concept provides a comparable flexibility, as an alternating magnetic field and an adjustable field gradient can be applied as known from electromagnetically driven MPI systems, and therefore yields high potential for an enlarged system. We present the idea of an arrangement of Halbach arrays and how to calculate the generated magnetic fields. Simulations for an exemplary geometry are provided to show the potential of the proposed setup.
AB - Magnetic particle imaging (MPI) is a new medical imaging technique visualizing the concentration distribution of superparamagnetic nanoparticles used as tracer material. MPI is not yet in clinical routine, since one of the challenges is the upscaling of scanners. Typically, the magnetic fields of MPI scanners are generated electromagnetically, resulting in an immense power consumption but providing high flexibility in terms of adjusting the field strengths and very fast image acquisition rates. Permanent magnets provide high flux densities and do not need any power supply. However, the flux density is not adjustable, and a mechanical movement is slow compared to electromagnetically varying fields. The MPI scanner concept proposed here uses permanent magnets and provides high flexibility, with the possibility to choose between fast overview scanning and detailed image acquisition. By mechanical rotation of magnetic rings in Halbach array configuration, it is possible to adjust the field or gradient strengths. The latter allows for determining the spatial resolution and the size of the field of view. A continuous mechanical rotation defines the coarseness of the scanning trajectory and image acquisition rate. This concept provides a comparable flexibility, as an alternating magnetic field and an adjustable field gradient can be applied as known from electromagnetically driven MPI systems, and therefore yields high potential for an enlarged system. We present the idea of an arrangement of Halbach arrays and how to calculate the generated magnetic fields. Simulations for an exemplary geometry are provided to show the potential of the proposed setup.
UR - http://www.scopus.com/inward/record.url?scp=85092674274&partnerID=8YFLogxK
U2 - 10.1088/1361-6560/ab7e7e
DO - 10.1088/1361-6560/ab7e7e
M3 - Journal articles
AN - SCOPUS:85092674274
SN - 0031-9155
VL - 65
JO - Physics in Medicine and Biology
JF - Physics in Medicine and Biology
IS - 19
M1 - 195014
ER -